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Drug-Induced Mesovarial Leiomyomas in the Rat—A Review and Additional Data

Autor: J. H. Weikel, W. A. Kelly, Ronald J Marler

Publikováno v: Journal of the American College of Toxicology. 12:13-22

Leiomyomas developed in the ovarian suspensory ligament (costo-uterine muscle) of rats after long-term treatment with several beta2-adrenoceptor stimulant drugs. The response was evidently related to excessive adrenergic stimulation of a tissue with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::da0ca83b04b5a48691fb247abfb7404a
https://doi.org/10.3109/10915819309140618

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A four-year evaluation of the chronic toxicity of megestrol acetate in dogs

Autor: L. W. Nelson, J. H. Weikel, F. E. Reno

Publikováno v: Toxicology and applied pharmacology. 33(3)

Megestrol acetate was administered orally to female beagle dogs for 4 yr at 0.01, 0.1, or 0.25 mg/kg/day. Chlormadinone acetate was given to a comparable group at 0.25 mg/kg. Decreased evidence of estrus was noted for all megestrol acetate and the ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebf625d9b2a8f2002e09b5eb401f9c2a
https://pubmed.ncbi.nlm.nih.gov/52913

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The metabolic fate of cyclophosphamide

Autor: J. A. Labudde, A. R. Torkelson, J. H. Weikel

Publikováno v: Drug metabolism reviews. 3(1)

(1975). The Metabolic Fate of Cyclophosphamide. Drug Metabolism Reviews: Vol. 3, No. 1, pp. 131-165.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c53f5cab1074deab6bd8ac28943d94c8
https://pubmed.ncbi.nlm.nih.gov/4214687

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