Zobrazeno 1 - 10 of 63 pro vyhledávání: '"J H, Pringle"'
1
Short stretches of rare codons regulate translation of the transcription factor ZEB2 in cancer cells
Autor: W R, Wan Makhtar, G, Browne, A, Karountzos, C, Stevens, Y, Alghamdi, A R, Bottrill, S, Mistry, E, Smith, M, Bushel, J H, Pringle, A E, Sayan, E, Tulchinsky
Publikováno v: Oncogene
Two proteins comprising the ZEB family of zinc finger transcription factors, ZEB1 and ZEB2, execute EMT programs in embryonic development and cancer. By studying regulation of their expression, we describe a novel mechanism that limits ZEB2 protein s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0f38474089e9f4c1ec74f9a25fcfae55
https://pubmed.ncbi.nlm.nih.gov/28783176
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2
A comparative study of digoxigenin, 2,4-dinitrophenyl, and alkaline phosphatase as deoxyoligonucleotide labels in non-radioisotopic in situ hybridisation
Autor: J. H. Pringle, Tom Brown, A. S. J. Stewart, Elaine M. Bailey, Catherine M. McKeen, S. J. Harper, John Feehally
AIM: To determine the optimum form of labelling and the most efficient reporter molecule for non-radioisotopic in situ hybridisation (ISH). METHODS: Nine deoxyoligonucleotides complementary to histone mRNA were synthesised and labelled either enzymat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb3fdc89d96d6227c1462f3d5ebdac1
https://doi.org/10.1136/jcp.50.8.686
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3
MicroRNAs are novel biomarkers of colorectal cancer
Autor: John Stuart Jameson, J. H. Pringle, Muhammad Imran Aslam, K. Taylor
Publikováno v: British Journal of Surgery. 96:702-710
Background Recent studies have identified unique small ribonucleic acids called microRNAs (miRNAs) in colonic tumour tissue and blood that may accurately diagnose the presence of colorectal cancer and help predict disease recurrence. This review expl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d6bd18d5f0665879f25223bcfdd419
https://doi.org/10.1002/bjs.6628
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4
Apoptosis in chronic viral hepatitis parallels histological activity: An immunohistochemical investigation using anti-activated caspase-3 and M30 Cytodeath antibody
Autor: Muna Ali Guzail, Jo L. McPartland, J H Pringle, Charles H. Kendall
Publikováno v: International Journal of Experimental Pathology. 86:19-24
Apoptosis is implicated as a major pathogenic mechanism in chronic hepatitis B and C. Previous studies of the relationship between apoptotic rates and histological necroinflammatory activity have produced conflicting results. Hepatocyte apoptosis was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f87adfc87913a11e6a8c17730cec735e
https://doi.org/10.1111/j.0959-9673.2005.00411.x
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5
There is more than one kind of myofibroblast: analysis of CD34 expression in benign, in situ, and invasive breast lesions
Autor: A Abraham, Rosemary A. Walker, J R A Phillips, J H Pringle, H Chauhan, JL Jones
Publikováno v: Journal of Clinical Pathology. 56:271-276
Smooth muscle actin (SMA) positive myofibroblasts have been implicated in tumour invasion; however, acquisition of SMA is not limited to peritumorous fibroblasts and other changes in fibroblasts may be more specifically related to the malignant envir
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145bedb66cf913201ca0a8cc7932e320
https://doi.org/10.1136/jcp.56.4.271
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6
Primary breast myoepithelial cells exert an invasion-suppressor effect on breast cancer cells via paracrine down-regulation of MMP expression in fibroblasts and tumour cells
Autor: J. L. Jones, Rosemary A. Walker, J H Pringle, Jacqueline A Shaw
Publikováno v: The Journal of Pathology. 201:562-572
In normal breast and ductal carcinoma in situ, myoepithelial cells form an incomplete layer separating the epithelial compartment from the stromal environment. Transition to invasive disease is marked by penetration of the myoepithelial-basement memb
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c288f794c494bda4d757037dde8f66
https://doi.org/10.1002/path.1483
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7
Vascular endothelial growth factor mRNA expression in minimal change, membranous, and diabetic nephropathy demonstrated by non-isotopic in situ hybridisation
Autor: Elaine M. Bailey, M J Bottomley, Steven J. Harper, John Feehally, Peter N. Furness, P. E. C. Brenchley, S Westwell, J. H. Pringle
Publikováno v: ResearcherID
AIM: To investigate vascular endothelial growth factor (VEGF) mRNA expression in glomerular disease in the context of heavy proteinuria. METHODS: Non-radioisotopic in situ hybridisation was performed using a cocktail of 12 deoxyoligonucleotides compl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9482c0eb46695ad365c74cfcb0ae02a8
https://doi.org/10.1136/jcp.52.10.735
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8
Glomerular expression of nephrin is decreased in acquired human nephrotic syndrome
Autor: Jacqueline A Shaw, L L Hall, J H Pringle, Peter N. Furness
Publikováno v: Nephrology Dialysis Transplantation. 14:1234-1237
the eVacement of foot processes represents a simpliBackground. Nephrin recently has been identified as a fication of architecture which demands massive remodputative adhesion molecule, expressed in the glomer- elling of the podocyte intercellular jun
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45df3cf0996a2ba8088b2a0a49927b4f
https://doi.org/10.1093/ndt/14.5.1234
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9
Numerical chromosomal aberrations in Hodgkin's disease detected by in situ hybridisation on routine paraffin sections
Autor: J A Shaw, A Gillies, I Lauder, J H Pringle
Publikováno v: Journal of Clinical Pathology. 50:553-558
AIMS: To visualise directly numerical chromosomal aberrations and polyploidy in both Hodgkin and Reed Sternberg (HRS) cells and background cells from cases of Hodgkin's disease using in situ hybridisation. METHODS: Non-isotopic DNA in situ hybridisat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614dc1cc6715898cb488725905ee8072
https://doi.org/10.1136/jcp.50.7.553
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10
Angiotropic lymphoma: report of a case with histiocytic features
Autor: D. A. Winfield, Carole A. Angel, K P West, John A. Snowden, J H Pringle
Publikováno v: Journal of Clinical Pathology. 50:67-70
Angiotropic lymphoma, also known as intravascular lymphomatosis, is characterised by widespread intravascular proliferation of malignant lymphoid cells, usually without evidence of focal disease. A case of a 52 year old man referred for investigation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e107fcf2da1d9d87cca8273e802567
https://doi.org/10.1136/jcp.50.1.67
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