Zobrazeno 1 - 10
of 93
pro vyhledávání: '"J H, Peacock"'
Publikováno v:
Arthroplasty, Vol 4, Iss 1, Pp 1-20 (2022)
Abstract Background To assess the Nickel sensitizing potential of total knee arthroplasty (TKA), explore the relationship between hypersensitivity and clinical outcomes, and evaluate the utility of skin patch testing pre- and/or postoperatively. Mate
Externí odkaz:
https://doaj.org/article/deadd9a581af44d489574e13a5f6e724
Autor:
Nick D. Clement, Irrum Afzal, Christian J. H. Peacock, Deborah MacDonald, Gavin J. Macpherson, James T. Patton, Vipin Asopa, David H. Sochart, Deiary F. Kader
Publikováno v:
Bone & Joint Open, Vol 3, Iss 7, Pp 573-581 (2022)
Aims: The aims of this study were to assess mapping models to predict the three-level version of EuroQoL five-dimension utility index (EQ-5D-3L) from the Oxford Knee Score (OKS) and validate these before and after total knee arthroplasty (TKA). Metho
Externí odkaz:
https://doaj.org/article/4c7d976482e44ccbacdf9edab11c9f14
Autor:
Paul Cornes, Clare Peckitt, Judith Earl, John Yarnold, Lone Gothard, Peter S. Mortimer, Emma Hall, Mary Woods, Julie MacLaren, J. H. Peacock
Publikováno v:
Radiotherapy and Oncology. 73:133-139
Background and purpose Treatment-induced arm lymphoedema is a common and distressing complication of curative surgery and radiotherapy for early breast cancer. A number of studies testing alpha-tocopherol (vitamin E) and pentoxifylline suggest eviden
Publikováno v:
Radiotherapy and Oncology. 63:213-216
Background and purpose : Small proportions of patients receiving radiotherapy develop marked long-term radiation damage. It is thought that this is due, at least in part, to intrinsic differences in cellular radiosensitivity, but the underlying mecha
Publikováno v:
British Journal of Cancer
Fibrosis in normal tissues is a common and dose-limiting late complication of radiotherapy at many cancer sites, but its pathogenesis is poorly understood. We undertook a controlled study of the effect of irradiation on the collagen production of fib
Publikováno v:
International Journal of Radiation Biology. 69:251-257
A flow cytometric technique utilizing the continuous incorporation of bromodeoxyuridine (BrdU) into asynchronous cells to measure radiation-induced cell cycle delay is described. Following the incorporation of the BrdU label the cells are stained wit
Publikováno v:
International Journal of Radiation Biology. 68:413-419
We have studied the role of glutathione (GSH) in determining radiation response in five human tumour and one human fibroblast cell line. GSH concentration was measured using the Tietze assay and compared with clonogenic survival following gamma-irrad
Publikováno v:
British Journal of Cancer
Large fluctuations in glutathione content were observed on a daily basis using the Tietze enzyme recycling assay in a panel of six human cell lines of varying radiosensitivity. Glutathione content tended to increase to a maximum during exponential ce
Publikováno v:
The British Journal of Radiology. 67:579-583
Fanconi anaemia (FA) is a rare inherited condition characterized by developmental abnormalities and progressive bone marrow failure, which requires bone marrow transplantation for successful treatment. This involves the use of alkylating agents and t
Publikováno v:
British Journal of Cancer
Cell killing of L1210 cells by cisplatin has been studied using flow cytometry and DNA gel electrophoresis. Ten hours after a supralethal dose of drug (100 microM), extensive apoptosis was induced. Cells were also susceptible to the induction of apop