Zobrazeno 1 - 10
of 43
pro vyhledávání: '"J H, Nuijens"'
Publikováno v:
The Netherlands journal of medicine. 77(7)
This case report describes a patient with a nearly fatal spontaneous haemorrhage of a hepatic adenoma that occurred in association with anabolic androgenic steroid (AAS) use. The patient was addicted to AAS and had been using exceptionally high dosag
Autor:
A. J. M. Eerenberg, H. Ten Cate, M C Minnema, W. A. Wuillemin, Dorina Roem, Joost C. M. Meijers, C. E. Hack, J. H. Nuijens
Publikováno v:
Blood, 85(6), 1517-1526. American Society of Hematology
From experiments with purified proteins, it has been concluded that factor XIa (FXIa) is inhibited in plasma mainly by alpha 1-antitrypsin (a1AT), followed by antithrombin III (ATIII), C1-inhibitor (C1Inh), and alpha 2-antiplasmin (a2AP). However, th
Publikováno v:
Thrombosis and Haemostasis. 67:644-648
SummaryWe developed a very sensitive assay for functional factor XII. This assay is based on the property of glass-bound factor XII to activate prekallikrein (PK) into kallikrein in factor XH-deficient plasma, which is assessed by measuring the forma
Autor:
J. J. Abbink, Strack van Schijndel Rj, A. J. M. Eerenberg, C. E. Hack, J. H. Nuijens, Lambertus G. Thijs, C. C. M. Huijbregts
Publikováno v:
Thrombosis and Haemostasis. 65:032-039
Alpha 2-macroglobulin (alpha 2 M) in vitro inhibits numerous proteinases that are generated during inflammatory reactions and therefore, probably plays an important role in diseases such as sepsis. To monitor the state of alpha 2 M in sepsis, we deve
Autor:
J. H. Nuijens, C. E. Hack, J. J. Abbink, A. J. M. Eerenberg, R.J.M. Strack van Schijndel, L. G. Thijs
Publikováno v:
Intensive Care Medicine. 16:S187-S191
Previously we studied levels of the cytokine IL-6 and activation of the complement and contact system and of neutrophils in a group of 48 patients with sepsis. Some of these inflammatory parameters appeared to be associated with a poor prognosis. Her
Publikováno v:
Advances in experimental medicine and biology. 501
Lactoferrin is an iron-binding glycoprotein abundantly present in human milk, and has been postulated both to increase and to decrease intestinal iron absorption. To examine this problem, the interaction of milk iron with pup hemoglobin was studied i
Publikováno v:
Advances in experimental medicine and biology. 501
Regulatory roles and a signaling receptor have been proposed for the milk protein lactoferrin (Lf), but none has been definitively characterized. Nichols and colleagues (1987) observed that human lactoferrin (hLf) stimulated thymidine incorporation i
Autor:
P J, Swart, M C, Harmsen, M E, Kuipers, A A, Van Dijk, B W, Van Der Strate, P H, Van Berkel, J H, Nuijens, C, Smit, M, Witvrouw, E, De Clercq, M P, de Béthune, R, Pauwels, D K, Meijer
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 5(12)
Previous studies have shown that acylated plasma and milk proteins with increased negative charge, derived from various animal and human sources, are potent anti-HIV compounds. The antiviral effects seemed to correlate positively with the number of n
Autor:
Y T, Wachtfogel, C, Kettner, C E, Hack, J H, Nuijens, T M, Reilly, R M, Knabb, U, Kucich, S, Niewiarowski, L H, Edmunds, R W, Colman
Publikováno v:
Thrombosis and haemostasis. 80(4)
Cardiopulmonary bypass causes hemorrhagic complications, and initiates a chemical and cellular inflammatory response. Contact of blood with synthetic surfaces leads to qualitative and quantitative alterations in platelets, neutrophils, complement, an
Publikováno v:
Advances in experimental medicine and biology. 443
We previously characterized a receptor of Mr 105,000 for human lactoferrin (hLf) on Jurkat human lymphoblastic T-cells. To delineate the role of R2R3R4R5 of hLf in the interaction with cells, we studied the binding of hLf variants obtained either by