Zobrazeno 1 - 3
of 3
pro vyhledávání: '"J H, Leif"'
Autor:
S W, Christianson, D L, Greiner, R A, Hesselton, J H, Leif, E J, Wagar, I B, Schweitzer, T V, Rajan, B, Gott, D C, Roopenian, L D, Shultz
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(8)
Genetic crosses produced NOD/LtSz mice doubly homozygous for the severe combined immunodeficiency (scid) mutation and the beta2m (B2m) null allele. Both NOD/LtSz-scid/scid and NOD/LtSz-scid/scid B2m(null) mice lacked mature lymphocytes and serum Ig.
Autor:
P A, Lowry, L D, Shultz, D L, Greiner, R M, Hesselton, E L, Kittler, C Y, Tiarks, S S, Rao, J, Reilly, J H, Leif, H, Ramshaw, F M, Stewart, P J, Quesenberry
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2(1)
Human lymphoematopoietic stem cells engraft in irradiated immunodeficient mice that are homozygous for the severe combined immunodeficiency (scid) mutation. Engraftment levels in C.B-17-scid/scid mice, however, have been low and transient, decreasing
Publikováno v:
In vivo (Athens, Greece). 10(1)
Human cord blood (HuCB) can colonize a murine fetal thymus organ culture (FTOC) and generate phenotypically immature (CD4+ CD8+) and mature (CD4+ CD8-; CD4- CD8+) T cells. We have used this model system to demonstrate that the human T cells that deve