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pro vyhledávání: '"J H, Heaton"'
Autor:
J. H. Heaton
Publikováno v:
Molecular Endocrinology. 6:53-60
Publikováno v:
The Journal of biological chemistry. 274(2)
Incubation of HTC rat hepatoma cells with the cyclic nucleotide analogue 8-bromo-cAMP results in a 3-fold increase in the rate of degradation of type-1 plasminogen activator-inhibitor (PAI-1) mRNA. Previous studies utilizing HTC cells stably transfec
Publikováno v:
The Journal of biological chemistry. 273(23)
Type-1 plasminogen activator-inhibitor (PAI-1) is a major physiologic inhibitor of plasminogen activation. Incubation of HTC rat hepatoma cells with the cyclic nucleotide analogue, 8-bromo-cAMP, causes a dramatic increase in tissue-type plasminogen a
Autor:
J H, Heaton, T D, Gelehrter
Publikováno v:
The Journal of biological chemistry. 252(9)
Amino acid starvation causes an adaptive increase in the initial rate of transport of selected neutral amino acids in an established line of rat hepatoma cells in tissue culture. After a lag of 30 min, the initial rate of transport of alpha-aminoisob
Publikováno v:
Biochimica et biophysica acta. 632(2)
Insulin stimulates a 2-fold increase in the amount of tyrosine aminotransferase and a 5-10-fold increase in the rate of amino acid transport in dexamethasone-treated rat hepatoma cells. In order to determine whether these effects are mediated by insu
Autor:
J H, Heaton, T D, Gelehrter
Publikováno v:
The Journal of biological chemistry. 256(23)
We have previously reported that incubation of rat hepatoma cells with insulin causes a complete and reversible loss of responsiveness to insulin. In order to determine the role of the insulin receptor in desensitization, we have examined the effect
Publikováno v:
The Journal of biological chemistry. 259(4)
We have reported previously that insulin causes a complete but reversible desensitization to insulin action in rat hepatoma HTC cells in tissue culture, and that this insulin resistance is mediated by postbinding mechanisms rather than receptor down-
Publikováno v:
The Journal of biological chemistry. 253(21)