Zobrazeno 1 - 10
of 38
pro vyhledávání: '"J H, Finke"'
Publikováno v:
Methods in molecular medicine. 53
Functional T cells are the central component of an effective antitumor immune response. However, in patients with renal cell carcinoma (RCC), the growth of antigenic tumors proceeds in the absence of significant T-cell responses, posing a distinct ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e94e98e7cfb9df007cbcd69746da6802
https://pubmed.ncbi.nlm.nih.gov/21318807
https://pubmed.ncbi.nlm.nih.gov/21318807
Publikováno v:
The Journal of Immunology. 149:529-534
The combination of IFN-gamma and IL-2 has been demonstrated to induce or promote transcription from selected inflammatory cytokine genes in both monocytes and macrophages. In the present report, we have evaluated the ability of these agents to activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96a428dd24ddef4dc845526c6573d68f
https://doi.org/10.4049/jimmunol.149.2.529
https://doi.org/10.4049/jimmunol.149.2.529
Autor:
P A, Cohen, L, Peng, J, Kjaergaard, G E, Plautz, J H, Finke, G K, Koski, B J, Czerniecki, S, Shu
Publikováno v:
Critical reviews in immunology. 21(1-3)
The T cells of many cancer patients are naturally sensitized to tumor-associated antigens (Ag), or they can readily be sensitized with vaccine maneuvers. In melanoma patients, the adoptive transfer of such T cells can often be causally linked to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7265b825117f2a89be751b00285abe13
https://pubmed.ncbi.nlm.nih.gov/11642606
https://pubmed.ncbi.nlm.nih.gov/11642606
Autor:
R G, Uzzo, V, Kolenko, C J, Froelich, C, Tannenbaum, L, Molto, A C, Novick, N H, Bander, R, Bukowski, J H, Finke
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(10)
The antitumor effect of T cells is executed either through CD95 or Perforin (PFN)/Granzyme B (GrB) pathways. Induction of apoptosis by either mode requires activation of caspase family members. However, recent studies have suggested that cell death c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65aff2865a172dfa371780b96da4b44d
https://pubmed.ncbi.nlm.nih.gov/11595725
https://pubmed.ncbi.nlm.nih.gov/11595725
Publikováno v:
Apoptosis : an international journal on programmed cell death. 6(6)
Alterations in intracellular Zn(2+) concentrations are believed to play a crucial role in modulating apoptosis. The observation that Zn(2+) deficiency can induce cell death both in vivo and in vitro has been attributed to the fact that exchange of Zn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9133f9330be9a1340817f1f880ae0e06
https://pubmed.ncbi.nlm.nih.gov/11595831
https://pubmed.ncbi.nlm.nih.gov/11595831
Autor:
J H, Finke, P, Rayman, R, George, C S, Tannenbaum, V, Kolenko, R, Uzzo, A C, Novick, R M, Bukowski
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7
Antitumor immunity fails to adequately develop in many cancer patients, including those with renal cell carcinoma (RCC). A number of different mechanisms have been proposed to explain the immune dysfunction observed in cancer patient T cells. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::690827e6ec1967884bb8f6047a892adf
https://pubmed.ncbi.nlm.nih.gov/11300495
https://pubmed.ncbi.nlm.nih.gov/11300495
Publikováno v:
Apoptosis : an international journal on programmed cell death. 5(1)
The majority of current anticancer therapies induce tumor cell death through the induction of apoptosis. Alterations in the apoptotic pathways may determine tumor resistance to these therapies. Activation of the proteolytic cascade involving caspase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08677cdc2ce28f9f05a200c972f07336
https://pubmed.ncbi.nlm.nih.gov/11227486
https://pubmed.ncbi.nlm.nih.gov/11227486
Autor:
P, Rayman, R G, Uzzo, V, Kolenko, T, Bloom, M K, Cathcart, L, Molto, A C, Novick, R M, Bukowski, T, Hamilton, J H, Finke
Publikováno v:
The cancer journal from Scientific American. 6
The development of an effective antitumor immune response is compromised in patients with renal cell carcinoma. Despite significant infiltration by T lymphocytes into renal tumors, no detectable induction of gene expression is associated with the gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ee5d3256adc479a0fe0173187265cd6
https://pubmed.ncbi.nlm.nih.gov/10685665
https://pubmed.ncbi.nlm.nih.gov/10685665
Autor:
R G, Uzzo, P, Rayman, V, Kolenko, P E, Clark, T, Bloom, A M, Ward, L, Molto, C, Tannenbaum, L J, Worford, R, Bukowski, R, Tubbs, E D, Hsi, N H, Bander, A C, Novick, J H, Finke
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(5)
Tumors may escape immune recognition and destruction through the induction of apoptosis in activated T lymphocytes. Results from several laboratories suggest that FasL (L/CD95L) expression in tumors may be responsible for this process. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f09ebf5ea645ca5357c7828c9318e2c
https://pubmed.ncbi.nlm.nih.gov/10353760
https://pubmed.ncbi.nlm.nih.gov/10353760
Autor:
R M, Bukowski, P, Rayman, R, Uzzo, T, Bloom, K, Sandstrom, D, Peereboom, T, Olencki, G T, Budd, D, McLain, P, Elson, A, Novick, J H, Finke
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(10)
Studies have demonstrated abnormalities of the CD3/T-cell antigen receptor (TCR) and pathways of signal transduction in T lymphocytes from animals and patients with advanced malignancy. Diminished expression of TCRzeta and p56(lck) that are associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd8ee1b35596ad6504df590c88a51436
https://pubmed.ncbi.nlm.nih.gov/9796963
https://pubmed.ncbi.nlm.nih.gov/9796963