Zobrazeno 1 - 10
of 13
pro vyhledávání: '"J H, Chace"'
Publikováno v:
The Journal of Immunology. 156:4570-4575
Microbial products released during bacterial infection induce cytokine-mediated inflammatory responses that can be protective, but excessive release of inflammatory cytokines may promote development of the sepsis syndrome. We examined the ability of
Publikováno v:
The Journal of Immunology. 156:558-564
Lymphocyte recognition of characteristic structural features in microbial DNA may contribute to immune defense by promoting protective immune responses. The dinucleotide CpG is significantly under-represented in vertebrate DNA and is usually methylat
Publikováno v:
The Journal of Immunology. 153:3369-3377
We have studied the relationship between B cell activation and the ability of IFN-gamma to inhibit B cell differentiation. The LPS activation of conventional and CD5+ B cells resulted in increased IFN-gamma R expression and increased the ability of I
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 156(12)
Microbial products released during bacterial infection induce cytokine-mediated inflammatory responses that can be protective, but excessive release of inflammatory cytokines may promote development of the sepsis syndrome. We examined the ability of
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(11)
The B-1a (CD5+) subset of B cells comprises the majority of B cells in the peritoneal cavity and is implicated in the pathogenesis of certain autoimmune diseases and lymphoproliferative disorders. When we stimulated purified B-1a cells with LPS, they
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 153(8)
We have studied the relationship between B cell activation and the ability of IFN-gamma to inhibit B cell differentiation. The LPS activation of conventional and CD5+ B cells resulted in increased IFN-gamma R expression and increased the ability of I
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(2)
Anti-CD4 has been extensively studied in murine models of autoimmunity and transplantation. The timing of anti-CD4 administration in these systems is critical because anti-CD4 effectively blocks primary T-dependent responses but does not diminish ong
Publikováno v:
Clinical immunology and immunopathology. 68(3)
We have analyzed the response of conventional and CD5+ B cells to the opposing signals delivered by LPS and interferon-gamma (IFN-gamma). Cultured CD5+ B cells secrete more IgM than conventional B cells in response to low concentrations of LPS. This
Publikováno v:
The Journal of Immunology. 141:3258-3262
We have studied hapten-binding cells from the spleens of normal and tolerant adult mice in terms of their ability to enlarge, proliferate, and differentiate into antibody-secreting cells. Tolerant B cells showed clear defects in intermediate activati
Publikováno v:
Biochemistry. 22:6341-6351
On the basis of primarily two types of observations, it has been suggested that the Na+-independent Ca2+ efflux mechanism of rat liver mitochondria is a passive Ca2+-2H+ exchanger. First, when a pulse of acid is added to a suspension of mitochondria