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Akademický článek

Hepatic gene transfer of the catalytic subunit of the apolipoprotein B mRNA editing enzyme results in a reduction of plasma LDL levels in normal and watanabe heritable hyperlipidemic rabbits

Autor: J Greeve, V K Jona, N R Chowdhury, M S Horwitz, J R Chowdhury

Publikováno v: Journal of Lipid Research, Vol 37, Iss 9, Pp 2001-2017 (1996)

Apolipoprotein (apo) B exists in two forms, the full length protein apoB-100 and the carboxyterminal-truncated apoB-48 that is synthesized in the intestine due to editing of the apoB mRNA which generates a premature stop codon. To determine whether g

Externí odkaz: https://doaj.org/article/96752c68c7e0402aac4012d545e76656

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Akademický článek

Apolipoprotein B mRNA editing in 12 different mammalian species: hepatic expression is reflected in low concentrations of apoB-containing plasma lipoproteins

Autor: J Greeve, I Altkemper, JH Dieterich, H Greten, E Windler

Publikováno v: Journal of Lipid Research, Vol 34, Iss 8, Pp 1367-1383 (1993)

Two different isoproteins are encoded by the apolipoprotein (apo) B gene, apoB-48 and apoB-100. ApoB-48, core component of intestinally derived chylomicrons, has an accelerated plasma turnover as compared with the full-length protein apoB-100. A post

Externí odkaz: https://doaj.org/article/8e6bc2850d4b4b169e388d82a3219a7b

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Akademický článek

Regulation of the hepatic removal of chylomicron remnants and beta-very low density lipoproteins in the rat.

Autor: S Jäckle, F Rinninger, J Greeve, H Greten, E Windler

Publikováno v: Journal of Lipid Research, Vol 33, Iss 3, Pp 419-429 (1992)

The contribution of the low density lipoprotein (LDL) receptor to the removal of chylomicron remnants was determined in vitro and in vivo by using interventions that up- or down-regulate the LDL receptor but not the LDL receptor-related protein (LRP)

Externí odkaz: https://doaj.org/article/6f03a27a98a042349d75611b27348b23

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