Zobrazeno 1 - 10
of 92
pro vyhledávání: '"J Garrigues"'
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007659 (2019)
The carboxy-terminal domain of the BBK32 protein from Borrelia burgdorferi sensu stricto, termed BBK32-C, binds and inhibits the initiating serine protease of the human classical complement pathway, C1r. In this study we investigated the function of
Externí odkaz:
https://doaj.org/article/00894cf20d844732a71ee2b0c2f1dda7
Proteolytic cascades comprise several important physiological systems, including a primary arm of innate immunity called the complement cascade. To safeguard against complement-mediated attack, the etiologic agent of Lyme disease, Borreliella burgdor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3eae6c3cb058104fd4e598b02cb4bd8
https://doi.org/10.1101/2022.08.17.504303
https://doi.org/10.1101/2022.08.17.504303
Autor:
Michael J. Pereira, Beau Wager, Ryan J. Garrigues, Eva Gerlach, Joshua D. Quinn, Alexander S. Dowdell, Marcia S. Osburne, Wolfram R. Zückert, Peter Kraiczy, Brandon L. Garcia, John M. Leong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(13)
Spirochetal pathogens, such as the causative agent of Lyme disease, Borrelia burgdorferi sensu lato, encode an abundance of lipoproteins; however, due in part to their evolutionary distance from more well-studied bacteria, such as Proteobacteria and
Publikováno v:
J Immunol
Complement evasion is a hallmark of extracellular microbial pathogens such as Borrelia burgdorferi, the causative agent of Lyme disease. Lyme disease spirochetes express nearly a dozen outer surface lipoproteins that bind complement components and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b8ed6afecf1bffbea88efde9694bd3
https://europepmc.org/articles/PMC8612984/
https://europepmc.org/articles/PMC8612984/
The complement system is a proteolytic cascade involving dozens of soluble and membrane-associated proteins that function in recognition, opsonization, and elimination of foreign or damaged cells of host origin. Complement evasion is a hallmark of ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8f00c78f0d170e987a1e3d491d47cbf
https://doi.org/10.1101/2021.01.21.427683
https://doi.org/10.1101/2021.01.21.427683
Autor:
Layla J. Garrigues
Publikováno v:
Integrative Health Nursing Interventions for Vulnerable Populations ISBN: 9783030600426
Social justice is the underlying principle of population health nursing and a fundamental nursing value. The tenets of social justice require nurses to maintain and demonstrate health-related ethical, moral, humanitarian, and legal principles. Nurses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fab946b27df81f95ad36ccba6cc5918
https://doi.org/10.1007/978-3-030-60043-3_2
https://doi.org/10.1007/978-3-030-60043-3_2
Autor:
Sambuddha, Banerjee, Ryan J, Garrigues, Mina N, Chanakira, Jacob J, Negron-Olivo, Yasmene H, Odeh, Anne M, Spuches, R, Martin Roop, Joshua Edison, Pitzer, Daniel W, Martin, Saumya, Dasgupta
Publikováno v:
J Inorg Biochem
Brucella is a zoonotic pathogen requiring iron for its survival and acquires this metal through the expression of several high-affinity uptake systems. Of these, the newly discovered ferrous iron transporter, FtrABCD, is proposed to take part in ferr
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007659 (2019)
PLoS Pathogens
PLoS Pathogens
The carboxy-terminal domain of the BBK32 protein from Borrelia burgdorferi sensu stricto, termed BBK32-C, binds and inhibits the initiating serine protease of the human classical complement pathway, C1r. In this study we investigated the function of
Autor:
Ryan J. Garrigues, Mina N. Chanakira, R. Martin Roop, Sambuddha Banerjee, Joshua E. Pitzer, Jacob J. Negron-Olivo, Daniel W. Martin, Yasmene H. Odeh, Saumya Dasgupta, Anne M. Spuches
Publikováno v:
Journal of Inorganic Biochemistry. 210:111162
Brucella is a zoonotic pathogen requiring iron for its survival and acquires this metal through the expression of several high-affinity uptake systems. Of these, the newly discovered ferrous iron transporter, FtrABCD, is proposed to take part in ferr
Autor:
Tracey J. Siegel, Layla J. Garrigues
Publikováno v:
Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society. 44(5)