Zobrazeno 1 - 10
of 22
pro vyhledávání: '"J G Spivack"'
Autor:
M. U. Fareed, J G Spivack, Nigel W. Fraser, Alasdair Roderick Maclean, J. S. O'Keefe, Tibor Valyi-Nagy, E. A. McKie, S. M. Brown, Richard M. Gesser, T. C. Nash
Publikováno v:
Journal of General Virology. 76:321-332
The herpes simplex virus type 1 (HSV-1) gamma 34.5 gene is located within a region that is transcriptionally active during latent HSV-1 infection. To determine whether the gamma 34.5 gene deletion affects latency-associated transcript (LAT) gene expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1512e03edaa885f0c020b98e4f4896
https://doi.org/10.1099/0022-1317-76-2-321
https://doi.org/10.1099/0022-1317-76-2-321
Autor:
M U Fareed, J G Spivack
Publikováno v:
Journal of Virology. 68:8071-8081
The herpes simplex virus type 1 (HSV-1) latency-associated transcripts (LATs) are dispensable for establishment and maintenance of latent infection. However, the LATs have been implicated in reactivation of the virus from its latent state. Since the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1416fd3c99de6762537fb6868b34310d
https://doi.org/10.1128/jvi.68.12.8071-8081.1994
https://doi.org/10.1128/jvi.68.12.8071-8081.1994
Autor:
J G, Spivack
Publikováno v:
Methods in molecular medicine. 10
Since the herpes simplex virus type 1 (HSV-1) genome has been sequenced and most HSV-1 RNAs are not spliced (1), detailed information about the structure of many HSV-1 RNAs can be obtained without the considerable time and effort that is required to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b085f890eb7e3d285b16ee4409952a98
https://pubmed.ncbi.nlm.nih.gov/21374231
https://pubmed.ncbi.nlm.nih.gov/21374231
The herpes simplex virus type 1 strain 17+ gamma 34.5 deletion mutant 1716 is avirulent in SCID mice
Autor:
M. U. Fareed, Tibor Valyi-Nagy, J. S. O'Keefe, Richard M. Gesser, Alasdair Roderick Maclean, J G Spivack, Nigel W. Fraser, S. M. Brown
Publikováno v:
The Journal of general virology. 75
Laboratory animal models are important tools for the identification of avirulent herpes simplex virus type 1 (HSV-1) strains which have potential for use in humans as vaccine strains or gene therapy vectors. We have studied an HSV-1 17+ variant, 1716
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11398b06050b61e1d65af2436f0a7a6f
https://pubmed.ncbi.nlm.nih.gov/8046409
https://pubmed.ncbi.nlm.nih.gov/8046409
Publikováno v:
Neuropathology and applied neurobiology. 20(3)
Restricted gene expression takes place during latent infection of herpes simplex virus type 1 (HSV-1) in the human peripheral nervous system and has been linked with viral reactivation. The state of HSV-1 gene expression in the central nervous system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4cf788c49fac8d67fd346dd00230c0
https://pubmed.ncbi.nlm.nih.gov/7936075
https://pubmed.ncbi.nlm.nih.gov/7936075
Autor:
M D Trousdale, J H Subak-Sharpe, Alasdair Roderick Maclean, Israel Steiner, S L Deshmane, S. M. Brown, J G Spivack, Nigel W. Fraser
Publikováno v:
Journal of virology. 65(12)
Many recent studies of latent herpes simplex virus type 1 (HSV-1) infections within the nervous system have focused on the diploid genes encoding the latency-associated transcripts (LATs). The impaired explant reactivation of LAT variants from mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b4926f57066c462e51fb424a693732
https://pubmed.ncbi.nlm.nih.gov/1658388
https://pubmed.ncbi.nlm.nih.gov/1658388
Publikováno v:
Journal of virology. 65(12)
Herpes simplex virus type 1 establishes latent infection in trigeminal ganglia of mice infected via the eye. A family of three colinear viral transcripts (LATs), 2.0, 1.5, and 1.45 kb, is present in latently infected ganglia. To characterize these LA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f8df48498df773d9a7cd2bdbf14e4d
https://pubmed.ncbi.nlm.nih.gov/1658375
https://pubmed.ncbi.nlm.nih.gov/1658375
Autor:
J G Spivack, Nigel W. Fraser, Richard M. Gesser, Zofia Wroblewska, Timothy M. Block, Tibor Valyi-Nagy, S L Deshmane, Rajeswari Natarajan
Publikováno v:
Current eye research.
The neurotropic herpes viruses, as typified by herpes simplex virus type 1, are noted for their ability to form latent infections. The latent infection differs from the acute infection both in gene expression and the physical state of the viral genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7171f065debb6b252a5bb24944642b77
https://pubmed.ncbi.nlm.nih.gov/1650659
https://pubmed.ncbi.nlm.nih.gov/1650659
Autor:
I Steiner, Timothy M. Block, S Deshmane, R P Lirette, J G Spivack, Michael T. McIntosh, Nigel W. Fraser
Publikováno v:
Journal of virology. 64(7)
The herpes simplex virus type 1 (HSV-1) latency-associated transcripts (LATs) accumulate in neuronal nuclei of latently infected ganglia. Explant reactivation kinetics of LAT deletion mutants in the mouse eye model have suggested a role for the LATs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87329f8e2fa976b6a119a5b19fed455
https://pubmed.ncbi.nlm.nih.gov/2161947
https://pubmed.ncbi.nlm.nih.gov/2161947
Autor:
Israel Steiner, Christopher Maurice Preston, C I Ace, S L Deshmane, J G Spivack, Nigel W. Fraser
Vmw65, a herpes simplex virus type 1 (HSV-1) tegument protein, in association with cellular proteins, transactivates viral immediate early genes. In order to examine the role of Vmw65 during acute and latent infection in vivo, a mutant virus (in1814)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15b5def7eaf959b6f827360c2c2b874
https://europepmc.org/articles/PMC249299/
https://europepmc.org/articles/PMC249299/
