Zobrazeno 1 - 10
of 20
pro vyhledávání: '"J G McKinnon"'
Autor:
Bernard Mark Smithers, Daniel F. Roses, Alistair J. Cochran, Mark B. Faries, William G. Kraybill, Constantine P. Karakousis, Omgo E. Nieweg, E. Paul, Mohammed Kashani-Sabet, Nicola Mozzillo, Robert Elashoff, J. G. McKinnon, C. A. Puleo, He-Jing Wang, Harald J. Hoekstra, John F. Thompson, Brendon J. Coventry, Donald L. Morton
Publikováno v:
New England Journal of Medicine, 370(7), 599-609. MASSACHUSETTS MEDICAL SOC
Sentinel-node biopsy, a minimally invasive procedure for regional melanoma staging, was evaluated in a phase 3 trial.We evaluated outcomes in 2001 patients with primary cutaneous melanomas randomly assigned to undergo wide excision and nodal observat
Autor:
John C. Rewcastle, Bryan J. Donnelly, R Baissalov, John C. Saliken, Ken Muldrew, J G McKinnon, George A. Sandison
Publikováno v:
Physics in Medicine and Biology. 45:N53-N59
Image guidance in cryotherapy is usually performed using ultrasound. Although not currently in routine clinical use, x-ray CT imaging is an alternative means of guidance that can display the full 3D structure of the iceball, including frozen and unfr
Autor:
J G McKinnon, Ken Muldrew, George A. Sandison, John C. Saliken, R Baissalov, Bryan J. Donnelly, John C. Rewcastle
Publikováno v:
Physics in Medicine and Biology. 45:1085-1098
A model is presented for treatment planning of multiprobe cryosurgery. In this model a thermal simulation algorithm is used to generate temperature distribution from cryoprobes, visualize isotherms in the anatomical region of interest (ROI) and provi
Publikováno v:
Cancer Immunology Immunotherapy. 32:38-44
Large numbers of cytotoxic T lymphocytes (CTL) could be generated from tumor-draining lymph nodes (DLN) from mice bearing PHS-5 tumor by culturing at low density with autologous tumor cell stimulators and 20 U/ml recombinant interleukin-2 (IL-2). Out
Publikováno v:
American Journal of Roentgenology. 166:853-855
Cryothemapy or cryosurgery, the destruction of tissue with freezing temperatures, has recently been revisited in treating abdominal and pelvic malignant tumors using sonogmaphic guidance and monitoring. Although it has been reported that “the contr
Publikováno v:
Journal of surgical oncology. 71(2)
Advances in the technology of cryomachines in the last 10 years have led to the development of both liquid nitrogen and argon-based Joule-Thompson cryomachines. Theoretical and practical evaluation of the CMS Accuprobe and the ENDOcare CRYOcare was p
Autor:
John C. Saliken, J G McKinnon, Bryan J. Donnelly, John C. Rewcastle, Leszek J. Hahn, George A. Sandison
Publikováno v:
Physics in medicine and biology. 43(12)
The optimal cooling parameters to maximize cell necrosis in different types of tissue have yet to be determined. However, a critical isotherm is commonly adopted by cryosurgeons as a boundary of lethality for tissue. Locating this isotherm within an
Publikováno v:
Journal of surgical oncology. 66(2)
During liver cryosurgical procedures, the authors observed seriously inconsistent rates of iceball growth implying inconsistent probe cooling rates. This inconsistency can lead to several problems, most importantly, loss of precision and reliability
Publikováno v:
Surgery. 113(5)
Cytotoxic T lymphocytes (CTL) have been shown to be useful for adoptive immunotherapy in malignancy. Traditional sources for CTL, such as tumor-infiltrating lymphocytes, have limitations. It would therefore be useful to develop a method of generating
Publikováno v:
Journal of Clinical Oncology. 28:e19016-e19016
e19016 Background: Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin tumor with high mortality rate and no definitive management guidelines published in the literature. Methods:...