Zobrazeno 1 - 7
of 7
pro vyhledávání: '"J G Gillum"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 40:1866-1869
Rifampin and rifabutin induce the metabolism of many drugs, which may result in subtherapeutic concentrations and failure of therapy. However, differences between rifabutin and rifampin in potency of induction, and the specific enzymes which are alte
Publikováno v:
Antimicrobial Agents and Chemotherapy. 39:1050-1053
Fluconazole inhibits cytochrome P-450-mediated enzymatic metabolism of several drugs. Since hepatic metabolism is partially responsible for 2',3'-dideoxyinosine (didanosine or ddI) elimination, fluconazole therapy may lead to increased ddI concentrat
Publikováno v:
Clinical Pharmacokinetics. 25:450-482
As new classes of antimicrobial drugs have become available, and new uses found for older drugs, pharmacokinetic drug interactions with antimicrobials have become more common. Macrolides, fluoroquinolones, rifamycins, azoles and other agents can inte
Autor:
J G Gillum, Harry P. Dalton, Ron E. Polk, M Turik, R Echols, M Towle, Kevin M. Harvey, J Ford, A H Heller, D S Israel
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:2193-2199
Fourteen adult males participated in a randomized three-way crossover study to compare the pharmacokinetics and serum bactericidal titers (SBTs) of 500 mg of ciprofloxacin (regimen A), 750 mg of ciprofloxacin (regimen B), and 400 mg of ofloxacin (reg
Publikováno v:
Clinical Infectious Diseases. 22:716-718
Publikováno v:
Pharmacotherapy. 15(2)
A 31-year-old, obese woman with extrameningeal cryptococcal disease was admitted to the Medical College of Virginia for antifungal therapy. Various physiologic variables influence flucytosine pharmacokinetics, and there are no guidelines for dosing t
Publikováno v:
Antimicrobial Agents and Chemotherapy. 40:1715-1716
Five adults completed this four-way randomized crossover study to compare the effects of oral treatment with ciprofloxacin, clarithromycin, and a combination of the two drugs on theophylline pharmacokinetics. The area under the concentration-time cur