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pro vyhledávání: '"J G Carver"'
We recently observed a patient in whom we suspected an interaction of azapropazone with phenytoin resulting in phenytoin toxicity. This and a report of a similar case led us to investigate the effect of azapropazone on steady-state plasma phenytoin c
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Publikováno v:
Clinical science (London, England : 1979). 93(3)
1. Previous electrophysiological studies have suggested the presence of KCa and Kv channels in human platelets. However, the pharmacology of these channels has not been defined. 2. We have studied potassium channels in human platelets by measuring th
Publikováno v:
Clinical science (London, England : 1979). 91(6)
1. Na+/K+/2Cl− co-transport mediates a bidirectional symport of Na+, K+ and Cl−. The important properties of the co-transport system are its requirement for Na+, K+ and Cl− and its inhibition by loop diuretics such as bumetanide. This co-transp
Publikováno v:
Clinical science (London, England : 1979). 91(6)
1. Na+/K+/2Cl- co-transport mediates a bidirectional symport of Na+, K+ and Cl-. The important properties of the co-transport system are its requirement for Na+, K+ and Cl- and its inhibition by loop diuretics such as bumetanide. This co-transporter
Publikováno v:
British Journal of Clinical Pharmacology. 15:727-734
We have investigated the interaction of azapropazone with phenytoin in five healthy volunteers. From steady-state plasma phenytoin concentrations of about 17 mumol/l there was at least a two-fold increase following the introduction of azapropazone. T
Autor:
J. G. Carver
Publikováno v:
Nuclear Applications. 6:526-532
Publikováno v:
Journal of reproduction and fertility. 51(2)
Autor:
J G Carver, J C Mott
Publikováno v:
The Journal of physiology. 276
1. In unanaesthetized preparations 6-14 days after catheterization, the concentration of renin substrate (AI 212 +/- 20 ng/ml. S.E. of mean) in the plasma of foetal lambs during the last third of gestation was significantly less than that of paired s
Autor:
Jeffrey K Aronson, J G Carver
Publikováno v:
Lancet (London, England). 1(8235)
Publikováno v:
British journal of clinical pharmacology. 8(2)
1 Measurements of the binding of 12‐alpha‐[3H]‐digoxin to the membranes of intact erythrocytes, erythrocyte 86rubidium uptake and intraerythrocytic sodium concentrations have been made in the red cells of various groups of patients‐those who