Zobrazeno 1 - 10
of 40
pro vyhledávání: '"J G Bieth"'
Publikováno v:
Applied Biochemistry and Biotechnology. 118:171-176
We studied the role of D158 in papain-like cysteine proteinases by using subtilisin Carlsberg, and its chemically modified analog thiolsubtilisin, by applying the proton inventory (PI) method and also by taking into account the pH profiles of the k c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::631076c7046bb17ede6e5dd99a2e4e42
https://doi.org/10.1385/abab:118:1-3:171
https://doi.org/10.1385/abab:118:1-3:171
Publikováno v:
Applied biochemistry and biotechnology. 118(1-3)
We studied the role of D158 in papain-like cysteine proteinases by using subtilisin Carlsberg, and its chemically modified analog thiolsubtilisin, by applying the proton inventory (PI) method and also by taking into account the pH profiles of the kca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4af1bf875ee88e46fa7b0a867c4b0287
https://pubmed.ncbi.nlm.nih.gov/15304747
https://pubmed.ncbi.nlm.nih.gov/15304747
Autor:
J G, Bieth
Publikováno v:
Journal de la Societe de biologie. 195(2)
Elastases are proteinases capable of solubilizing fibrous elastin. They may belong to the class of serine proteinases, cysteine proteinases and metalloproteinases. Mammalian elastases occur mainly in the pancreas and the phagocytes. Among non-mammali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e513faa70af4d56c4dab0cd0a293b63a
https://pubmed.ncbi.nlm.nih.gov/11723830
https://pubmed.ncbi.nlm.nih.gov/11723830
Publikováno v:
European journal of biochemistry. 259(3)
Human cysteine protease cathepsin L was inactivated at acid pH by a first-order process. The inactivation rate decreased with increasing concentrations of a small synthetic substrate, suggesting that substrates stabilize the active conformation. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b27b63212d6365d268ef42701cb6428
https://pubmed.ncbi.nlm.nih.gov/10092883
https://pubmed.ncbi.nlm.nih.gov/10092883
Autor:
J G, Bieth
Publikováno v:
Methods in enzymology. 248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::737ce44d289a78f50cbc758e0ab666a4
https://pubmed.ncbi.nlm.nih.gov/7674947
https://pubmed.ncbi.nlm.nih.gov/7674947
Autor:
M, Padrines, J G, Bieth
Publikováno v:
Biochimica et biophysica acta. 1163(1)
This paper investigates the catalytic activity of Pseudomonas aeruginosa elastase using the bait region of the alpha 1-proteinase inhibitor as a substrate. The bacterial enzyme cleaves the Pro357-Met358 bond of the wild-type inhibitor and the recombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc8a774ad3b21ca0c42dbe4e1a832d86
https://pubmed.ncbi.nlm.nih.gov/8476930
https://pubmed.ncbi.nlm.nih.gov/8476930
Publikováno v:
Biochimica et biophysica acta. 1118(2)
Unlike human neutrophil elastase or porcine and rat pancreatic elastases, human pancreatic elastase is rapidly inhibited by oxidized alpha 1-proteinase inhibitor. The second-order association-rate constant for the reaction of the oxidized inhibitor w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d26b69bf429c8a7740a2d8a0f0057a4
https://pubmed.ncbi.nlm.nih.gov/1730036
https://pubmed.ncbi.nlm.nih.gov/1730036
Autor:
J. G. Bieth
Publikováno v:
Biochemistry of Pulmonary Emphysema ISBN: 9781447137733
It is commonly acknowledged that neutrophil elastase (NE) is responsible for lung elastin degradation that leads to emphysema.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a88ad03c087d510b61b2ec22045d5a4
https://doi.org/10.1007/978-1-4471-3771-9_4
https://doi.org/10.1007/978-1-4471-3771-9_4
Publikováno v:
The Journal of biological chemistry. 266(23)
Heparin depresses the second-order rate constant ka for the inhibition of neutrophil elastase by alpha 1-proteinase inhibitor. High molecular mass heparin decreases ka from 1.3 x 10(7) M-1 s-1 to a limit of 4.6 x 10(4) M-1 s-1. Low molecular mass hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4a44fb1d85c5900ed6318e2aa22c46c
https://pubmed.ncbi.nlm.nih.gov/1869557
https://pubmed.ncbi.nlm.nih.gov/1869557
Autor:
K, Frommherz, J G, Bieth
Publikováno v:
Advances in experimental medicine and biology. 297
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45c389af06a9d3fb8d943a5dafe93983
https://pubmed.ncbi.nlm.nih.gov/1662871
https://pubmed.ncbi.nlm.nih.gov/1662871