Zobrazeno 1 - 6
of 6
pro vyhledávání: '"J G Adams rd"'
Autor:
Martin H. Steinberg, M Plonczynski, M. B. Coleman, Z H Lu, C M Smith nd, J G Adams rd, A Harrell
Publikováno v:
The Journal of clinical investigation. 95(2)
We studied the molecular basis of transfusion-dependent hemolytic anemia in an infant who rapidly developed the phenotype of beta thalassemia major. DNA sequence of one beta-globin gene of the proband revealed two mutations, one for the moderately un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8565ab5db2c660ce4a2f952a6bd510b4
https://pubmed.ncbi.nlm.nih.gov/7860732
https://pubmed.ncbi.nlm.nih.gov/7860732
Autor:
Alan N. Schechter, J G Adams rd, R Nicholson, C T Noguchi, Martin H. Steinberg, A K Gupta, Kent Kirchner
Publikováno v:
The Journal of clinical investigation. 88(6)
A defect in urine concentrating ability occurs in individuals with sickle cell trait (HbAS). This may result from intracellular polymerization of sickle hemoglobin (HbS) in erythrocytes, leading to microvascular occlusion, in the vasa recta of the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6958be092192b665d9a95e2deb1ca444
https://pubmed.ncbi.nlm.nih.gov/1752955
https://pubmed.ncbi.nlm.nih.gov/1752955
Autor:
R L Baehner, Martin H. Steinberg, B G Forget, G A Tsistrakis, J G Adams rd, Laurence A. Boxer
Publikováno v:
Journal of Clinical Investigation. 63:931-938
Hemoglobin (Hb) Indianapolis is an extremely labile beta-chain variant, present in such small amounts that it was undetectable by usual techniques. Clinically, it produces the phenotype of severe beta-thalassemia. Biosynthetic studies showed a beta:a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d45121d0cf13a6e48408aecadf16ba
https://doi.org/10.1172/jci109393
https://doi.org/10.1172/jci109393
Autor:
J G Adams rd, A Altman, Elaine Coupal, Barry L. Tonkonow, Edward J. Benz, Laurence A. Boxer, B W Berman, Thomas D. Coates
Publikováno v:
Journal of Clinical Investigation. 68:118-126
Inheritance of the gene for betaE-globin is associated with hypochromia and microcytosis, reminiscent of typical heterozygous beta-thalassemia. Patients with hemoglobin (Hb)E-beta-thalassemia exhibit clinical phenotypes of severe beta-thalassemia, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbfdbdc52c59a7182811ac96cf85788
https://doi.org/10.1172/jci110226
https://doi.org/10.1172/jci110226
Publikováno v:
The Journal of clinical investigation. 80(1)
An American black woman was found to have the phenotype of moderately severe alpha-thalassemia normally associated with the loss of two to three alpha-globin genes despite an alpha-globin gene map that demonstrated the loss of only a single alpha-glo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81615506c442756cabf2fc0e0d6abb6c
https://pubmed.ncbi.nlm.nih.gov/3597771
https://pubmed.ncbi.nlm.nih.gov/3597771
Autor:
W T Morrison, Martin H. Steinberg, J G Adams rd, R. F. Rieder, D J Pullen, A Ibrahim, R Abney
Hemoglobin Mississippi (HbMS: beta 44ser----cys) has anomalous properties that include disulfide linkages with normal beta-, delta-, gamma-, and alpha-chains, and the formation of high molecular weight multimers. While heterozygotes for HbMS are clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ed5488356df92de5cde4d1ee362e8d
https://europepmc.org/articles/PMC424211/
https://europepmc.org/articles/PMC424211/
