Zobrazeno 1 - 10
of 177
pro vyhledávání: '"J G, Webster"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract While changes in RNA splicing have been extensively studied in hepatocellular carcinoma (HCC), no studies have systematically investigated changes in RNA splicing during earlier liver disease. Mouse studies have shown that disruption of RNA
Externí odkaz:
https://doaj.org/article/43b92554437d4ba486ed097c198b928e
Autor:
Dongjie Wang, Wen Li, Natalie Albasha, Lindsey Griffin, Han Chang, Lauren Amaya, Sneha Ganguly, Liping Zeng, Bora Keum, José M. González-Navajas, Matt Levin, Zohreh AkhavanAghdam, Helen Snyder, David Schwartz, Ailin Tao, Laela M. Boosherhri, Hal M. Hoffman, Michael Rose, Monica Valeria Estrada, Nissi Varki, Scott Herdman, Maripat Corr, Nicholas J. G. Webster, Eyal Raz, Samuel Bertin
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-24 (2023)
Abstract Background Individuals with certain chronic inflammatory lung diseases have a higher risk of developing lung cancer (LC). However, the underlying mechanisms remain largely unknown. Here, we hypothesized that chronic exposure to house dust mi
Externí odkaz:
https://doaj.org/article/f506227a08414d8eb5c6d5a982b91b04
Autor:
Arwa Kurabi, Dong Gu Hur, Kwang Pak, Madeline Gibson, Nicholas J. G. Webster, Andrew Baird, Brian P. Eliceiri, Allen F. Ryan
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Otitis media (OM), the most common disease of childhood, is typically characterized by bacterial infection of the middle ear (ME). Prominent features of OM include hyperplasia of the ME mucosa, which transforms from a monolayer of simple squamous epi
Externí odkaz:
https://doaj.org/article/60527e3c4e484944810f0de33810404d
Autor:
Deepak Kumar, Manasi Das, Alexis Oberg, Debashis Sahoo, Panyisha Wu, Consuelo Sauceda, Lily Jih, Lesley G. Ellies, Magda T. Langiewicz, Supriya Sen, Nicholas J. G. Webster
Publikováno v:
Advanced Science, Vol 9, Iss 21, Pp n/a-n/a (2022)
Abstract Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Serine‐arginine rich splicing factor 3 (SRSF3) plays a critical role in hepatocyte function and its loss in mice promotes chronic liver damage and leads to HCC. Hepa
Externí odkaz:
https://doaj.org/article/62d5642666cc412fa26063b587ba6a76
Autor:
Manasi Das, Lesley G. Ellies, Deepak Kumar, Consuelo Sauceda, Alexis Oberg, Emilie Gross, Tyler Mandt, Isabel G. Newton, Mehak Kaur, Dorothy D. Sears, Nicholas J. G. Webster
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Obesity and its associated metabolic changes, including hyperinsulinemia and aberrant circadian rhythms, increases the risk for a variety of cancers including postmenopausal breast cancer. Here, the authors show that restricting when mice eat, but no
Externí odkaz:
https://doaj.org/article/a2944ae436f340f4a94b7c20729f5a09
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Alternative RNA splicing is a process by which introns are removed and exons are assembled to construct different RNA transcript isoforms from a single pre-mRNA. Previous studies have demonstrated an association between dysregulation of RNA splicing
Externí odkaz:
https://doaj.org/article/300b3e3bec4842328c3883bfcb55e50e
Autor:
Nicholas J. G. Webster
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Non-alcoholic fatty liver disease (NAFLD) is becoming increasingly prevalent due to the worldwide obesity epidemic and currently affects one-third of adults or about one billion people worldwide. NAFLD is predicted to affect over 50% of the world’s
Externí odkaz:
https://doaj.org/article/59f24c837e3b40a2ac6c57195b1bc7bd
Autor:
Isabel G. Newton, Deepak Kumar, Lesley G. Ellies, Tyler Mandt, Nicholas J. G. Webster, Dorothy D. Sears, Manasi Das, Mehak Kaur, Alexis Oberg, Consuelo Sauceda, Emilie Gross
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature communications, vol 12, iss 1
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications
Accumulating evidence indicates that obesity with its associated metabolic dysregulation, including hyperinsulinemia and aberrant circadian rhythms, increases the risk for a variety of cancers including postmenopausal breast cancer. Caloric restricti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bee7e08db6adaf00ba3c09d30eb6cc1
https://doaj.org/article/a2944ae436f340f4a94b7c20729f5a09
https://doaj.org/article/a2944ae436f340f4a94b7c20729f5a09
Autor:
Sushil K. Mahata, Sumana Mahata, Teresa Pasqua, Ennio Avolio, Kechun Tang, Gautam Bandyopadhyay, Nicholas J. G. Webster
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97a8ffee9d095be6d1ae08aeb8658b3b
https://doi.org/10.1096/fasebj.2022.36.s1.r3297
https://doi.org/10.1096/fasebj.2022.36.s1.r3297
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158597 (2016)
Gonadotropin-releasing hormone (GnRH), a neuropeptide released from a small population of neurons in the hypothalamus, is the central mediator of the hypothalamic-pituitary-gonadal axis, and is required for normal reproductive development and functio
Externí odkaz:
https://doaj.org/article/b86b94e9533b43c1b8196482e716c11d