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pro vyhledávání: '"J G, Teodoro"'
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 7(12)
Studies were carried out to determine the effects of introducing p53 using an adenovirus gene transfer vector into p53 null human Saos-2 osteogenic carcinoma cells. Expression of p53 led to cell death within 30-40 h. The morphology of these cells as
Autor:
C A, Boulakia, G, Chen, F W, Ng, J G, Teodoro, P E, Branton, D W, Nicholson, G G, Poirier, G C, Shore
Publikováno v:
Oncogene. 12(3)
The E1A oncoproteins of adenovirus type 5 are potent inducers of apoptotic cell death. To manifest growth promoting and transforming properties, therefore, E1A requires the co-expression of a suppressor of apoptosis. During normal viral infection, th
Publikováno v:
Oncogene. 11(3)
E1A of human adenovirus type 5 (Ad5) encodes proteins of 289 and 243 residues (289R and 243R) which differ only by the 46 amino acid CR3 region known to activate expression of certain cellular and early viral genes. E1A proteins also induce DNA synth