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The Interaction of Protein S with the Phospholipid Surface Is Essential for the Activated Protein C-independent Activity of Protein S

Autor: R M Bertina, C. van 't Veer, M. Van Wijnen, B. N. Bouma, Joost C. M. Meijers, Pieter H. Reitsma, J. G. Stam

Publikováno v: Thrombosis and haemostasis, 76(3), 397-403. Schattauer GmbH

SummaryProtein S is a vitamin-K dependent glycoprotein involved in the regulation of the anticoagulant activity of activated protein C (APC). Recent data showed a direct anticoagulant role of protein S independent of APC, as demonstrated by the inhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0b4254576097644f0d6b3520be8bb6
https://doi.org/10.1055/s-0038-1650590

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Antibiotics: ��-Lactamase Inhibitors

Autor: J. G. Stam

Publikováno v: Van Nostrand's Encyclopedia of Chemistry

Mechanistic Aspects of β-Lactamase Inhibition β-Lactam-Based Inhibitors Economic Aspects Keywords: acetylene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03f42711a729fe9bc6833a330f19b5da
https://doi.org/10.1002/0471740039.vec0227

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β‐Lactamase Inhibitors

Autor: J. G. Stam

Publikováno v: Kirk-Othmer Encyclopedia of Chemical Technology

The antibacterial effectiveness of penicillins, cephalosporins, and other β-lactam antibiotics depends on the inactivation of transpeptidases involved in bacterial cell wall synthesis. Bacteria that are resistant to β-lactam antibiotics often produ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bdabfa5c3eb136998d92d6cc9208853e
https://doi.org/10.1002/0471238961.1201032019200113.a01

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Characterization of mini-protein S, a recombinant variant of protein S that lacks the sex hormone binding globulin-like domain

Autor: Bonno N. Bouma, Rogier M. Bertina, Pieter H. Reitsma, Joost C. M. Meijers, J. G. Stam, G. T. G. Chang, M. Van Wijnen

Publikováno v: The Biochemical journal. 330

Protein S is a vitamin K-dependent glycoprotein involved in the regulation of the anticoagulant activity of activated protein C (APC). Also, an anticoagulant role for protein S, independent of APC, has been described. Protein S has a unique C-termina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b3da918d5f980b7081cc946d76bce6
https://pubmed.ncbi.nlm.nih.gov/9461535

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The interaction of protein S with the phospholipid surface is essential for the activated protein C-independent activity of protein S

Autor: M, van Wijnen, J G, Stam, C, van't Veer, J C, Meijers, P H, Reitsma, R M, Bertina, B N, Bouma

Publikováno v: Thrombosis and haemostasis. 76(3)

Protein S is a vitamin-K dependent glycoprotein involved in the regulation of the anticoagulant activity of activated protein C (APC). Recent data showed a direct anticoagulant role of protein S independent of APC, as demonstrated by the inhibition o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::272e6bc1353770f9c24056b8d2ca40eb
https://pubmed.ncbi.nlm.nih.gov/8883277

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ChemInform Abstract: BRONCHODILATOR AND ANTIULCER PHENOXYPYRIMIDINONES

Autor: H. J. Hess, J. G. Stam, Christopher A. Lipinski, J. N. Pereira, N. R. Ackerman

Publikováno v: Chemischer Informationsdienst. 12

Series of 5-phenoxy-2(1H)-pyrimidinones, 5-phenoxy-4(3H)-pyrimidinones, and related compounds were prepared in a follow-up of a lead prepared as a potential cyclic nucleotide regulating agent. Compounds were evaluated for bronchodilator activity in h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f57af54b8d9d48522b6128769f7350b0
https://doi.org/10.1002/chin.198109264

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