Zobrazeno 1 - 10
of 79
pro vyhledávání: '"J G, Michael"'
Publikováno v:
BioDrugs. 9:261-270
Subcutaneous immunotherapy has been used successfully to treat atopic diseases for many years. However, its use is associated with several problems, the most bothersome being systemic allergic reactions. This has led to evaluation of alternative meth
Autor:
J P Vasilakos, J G Michael
Publikováno v:
The Journal of Immunology. 150:2346-2355
Cytotoxic T cells were induced in vivo by immunizing C57BL/6 mice with a single dose of a short synthetic peptide representing amino acid residues 497-507 from HSV-1 glycoprotein B. Primed lymph node cells did not require in vitro boosting with pepti
Publikováno v:
Cellular Immunology. 127:67-77
Preparations of bovine serum albumin (BSA) were cationized by substituting anionic side chain carboxyl groups with polycationic aminoethylamide groups. Different degrees of substitution were obtained by varying the reaction time. Mice immunized with
Publikováno v:
Pediatric emergency care. 15(4)
Autor:
Z Y Zhang, J G Michael
Publikováno v:
The Journal of Immunology. 144:4163-4165
The role of murine epithelial cells from small intestine (IEC) in orally induced immune unresponsiveness has been investigated. Murine IEC were shown to express a relatively low level of class II MHC Ag and were incapable of presenting BSA to Ag-spec
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(1)
Previous studies have suggested that oral tolerance induction by low doses of Ag is mediated by inhibitory cytokines, particularly TGF-beta 1. To examine the roles of TGF-beta 1 and other inhibitory cytokines in the induction of oral tolerance, TGF-b
Publikováno v:
Vaccine. 14(13)
Oral administration of soluble protein antigen, ovalbumin (OVA), encapsulated by an acid-resistant acrylic polymer, induced a strong immune response in BDF1 mice. Mice fed the encapsulated OVA showed activation of antigen-specific IgA, IgG and IgG1 i
Autor:
S L, Jain, J G, Michael
Publikováno v:
Advances in experimental medicine and biology.
1. Pepsin-digested form of OVA has approximately the same molecular weight as native OVA, but differs in charge and isoelectric focusing point. 2. Pepsin-treated OVA retains most of the native OVA T- and B-cell determinants. 3. Delayed-type hypersens
Autor:
J G, Michael
Publikováno v:
Cellular immunology. 138(1)
Cationization of bovine serum albumin (BSA) causes a profound increase in its immunogenicity. To establish if immunoregulatory properties of an immunosuppressive peptide are affected by cationization, a BSA peptide, a.a. 506-583, was cationized and t
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 20(6)
Summary Fragments of short ragweed extract were prepared by peptic digestion and fractionated by molecular exclusion chromatography. We focused on fragmenting a ragweed fraction that was enriched for Amb a I. Digestion products in the molecular weigh