Zobrazeno 1 - 10
of 61
pro vyhledávání: '"J G, Liehr"'
Publikováno v:
Annals of the New York Academy of Sciences. 922:320-323
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fc6461cdb9cc2c2bfd87c11119659a
https://doi.org/10.1111/j.1749-6632.2000.tb07054.x
https://doi.org/10.1111/j.1749-6632.2000.tb07054.x
Autor:
J. G. Liehr
Publikováno v:
Endocrine Reviews. 21:40-54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::300e7718d3133ce14c9da0d5bf263fb0
https://doi.org/10.1210/er.21.1.40
https://doi.org/10.1210/er.21.1.40
Publikováno v:
Pure and Applied Chemistry. 70:1747-1758
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aacbd1f821a7cadfc2a9501229098c57
https://doi.org/10.1351/pac199870091747
https://doi.org/10.1351/pac199870091747
Autor:
James D. Yager, J G Liehr
Publikováno v:
Annual Review of Pharmacology and Toxicology. 36:203-232
In western society, the causes of several cancers--including breast, endometrium, ovary, liver, and prostate--have been linked to inappropriate and/or prolonged exposure to synthetic or endogenous steroidal hormones. In this review, we discuss the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1beb8c6c7cd98c3be86d056d20e20074
https://doi.org/10.1146/annurev.pa.36.040196.001223
https://doi.org/10.1146/annurev.pa.36.040196.001223
Autor:
J. G. Liehr, Z. Cao
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9b2a1d20227490fd374f2777fc3a71f
https://doi.org/10.1002/chin.199722203
https://doi.org/10.1002/chin.199722203
Autor:
C R, Jefcoate, J G, Liehr, R J, Santen, T R, Sutter, J D, Yager, W, Yue, S J, Santner, R, Tekmal, L, Demers, R, Pauley, F, Naftolin, G, Mor, L, Berstein
Publikováno v:
Journal of the National Cancer Institute. Monographs. (27)
Estrogen exposure represents the major known risk factor for development of breast cancer in women and is implicated in the development of prostate cancer in men. Human breast tissue has been shown to be a site of oxidative metabolism of estrogen due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9b9e1d6b7e85092ddb6d7a5c0f8e2d36
https://pubmed.ncbi.nlm.nih.gov/10963622
https://pubmed.ncbi.nlm.nih.gov/10963622
Publikováno v:
Journal of the National Cancer Institute. Monographs. (27)
Estrogens induce tumors in laboratory animals and have been associated with breast and uterine cancers in humans. In relation to the role of estrogens in the induction of cancer, we examine formation of DNA adducts by reactive electrophilic estrogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85bdc8518ccb505e20b1cb9263e0a8d5
https://pubmed.ncbi.nlm.nih.gov/10963621
https://pubmed.ncbi.nlm.nih.gov/10963621
Autor:
R R, Newbold, J G, Liehr
Publikováno v:
Cancer research. 60(2)
Catechol estrogens may mediate estrogen-induced carcinogenesis because 4-hydroxyestradiol induces DNA damage and renal tumors in hamsters, and this metabolite is formed in the kidney and estrogen target tissues by a specific estrogen 4-hydroxylase. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::039e35d1a4a36990e7d50093e8dd0d65
https://pubmed.ncbi.nlm.nih.gov/10667565
https://pubmed.ncbi.nlm.nih.gov/10667565
Publikováno v:
International Journal of Oncology.
We examined the effects of estradiol (E2), the natural estrogenic hormone, on the structure and expression of DNA polymerase beta (DNA pol beta), a DNA repair gene, from E2-induced primary kidney tumors of twelve Syrian hamsters, their metastases, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd88c1c07d618fb1a084446b510d001
https://doi.org/10.3892/ijo.15.2.353
https://doi.org/10.3892/ijo.15.2.353
Autor:
S F, Sarabia, J G, Liehr
Publikováno v:
Molecular carcinogenesis. 24(4)
The conversion of a palindromic sequence, GGTCTnnnAGACC, in the 5'-flanking region of the murine c-fos proto-oncogene into a functional estrogen-response element by a single base change into GGTC(A/G)nnnAGACC has previously been postulated [Nawaz et
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7967dd785eee58615826f57a4fe1a5c6
https://pubmed.ncbi.nlm.nih.gov/10326862
https://pubmed.ncbi.nlm.nih.gov/10326862