Zobrazeno 1 - 10 of 16 pro vyhledávání: '"J G, Krueger"'
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Akademický článek
The Impact of Body Mass Index Upon the Efficacy of Adalimumab in Hidradenitis Suppurativa
Autor: John W. Frew, N. Singh, C. S. Jiang, R. Vaughan, J. G. Krueger
Publikováno v: Frontiers in Medicine, Vol 8 (2021)
Elevated BMI in Hidradenitis Suppurativa is associated with decreased response to Adalimumab therapy. BMI is proposed to segregate distinct disease subtypes. It remains unresolved whether a threshold BMI exists above which increased dosages may provi
Externí odkaz: https://doaj.org/article/f6d6060371734047afa9e7a62aeb9df8
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2
P504 Guselkumab, an IL-23p19 subunit–specific monoclonal antibody, binds CD64+ myeloid cells and potently neutralises IL-23 produced from the same cells
Autor: R Atreya, M T Abreu, J G Krueger, K Eyerich, K Sachen, C Greving, D Hammaker, P Bao, E Lacy, I Sarabia, J Deming, M M Elloso, C Ritchlin, I B McInnes, M Allez, A Fourie
Publikováno v: Journal of Crohn's and Colitis. 17:i634-i635
Background Monoclonal antibodies targeting the interleukin (IL)-23p19 subunit are effective in the treatment of inflammatory bowel diseases (IBD), but have different molecular attributes that may translate to differences in clinical efficacy. Within
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::481b85509fe9457f7c3c46b11cdb90b2
https://doi.org/10.1093/ecco-jcc/jjac190.0634
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3
Role of the immune system and immunological circuits in psoriasis
Autor: A, Jabbari, L M, Johnson-Huang, J G, Krueger
Publikováno v: Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia. 146(1)
Psoriasis vulgaris is a chronic skin disease in which our understanding of the pathogenesis has substantially grown in recent years. Our current appreciation of the role of the immune system is that it plays a necessary and driving role in the diseas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::25903a9459dfc00d8689f415be01aee3
https://pubmed.ncbi.nlm.nih.gov/21317854
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4
Two considerations for patients with psoriasis and their clinicians: what defines mild, moderate, and severe psoriasis? What constitutes a clinically significant improvement when treating psoriasis?
Autor: G G, Krueger, S R, Feldman, C, Camisa, M, Duvic, J T, Elder, A B, Gottlieb, J, Koo, J G, Krueger, M, Lebwohl, N, Lowe, A, Menter, W L, Morison, J H, Prystowsky, J L, Shupack, J R, Taylor, G D, Weinstein, T L, Barton, T, Rolstad, R M, Day
Publikováno v: Journal of the American Academy of Dermatology. 43(2 Pt 1)
The definitions of psoriasis severity and clinically significant improvement in psoriasis are used to classify treatments, obtain Food and Drug Administration approval, and determine product labeling and reimbursement. The Medical Advisory Board of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d66fdf74edf353a1067b478255fd8f53
https://pubmed.ncbi.nlm.nih.gov/10906652
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5
The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, defining TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients
Autor: L M, Austin, M, Ozawa, T, Kikuchi, I B, Walters, J G, Krueger
Publikováno v: The Journal of investigative dermatology. 113(5)
Psoriasis vulgaris is a skin disease potentially mediated by pro-inflammatory cytokines produced by type 1 lesional T cells. The capability of individual T cells to produce these cytokines in lesional skin is not known. In this study we measured the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d95f1d791067796afb734c25f1d795a4
https://pubmed.ncbi.nlm.nih.gov/10571730
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7
Narrowband UV-B produces superior clinical and histopathological resolution of moderate-to-severe psoriasis in patients compared with broadband UV-B
Autor: T R, Coven, L H, Burack, R, Gilleaudeau, M, Keogh, M, Ozawa, J G, Krueger
Publikováno v: Archives of dermatology. 133(12)
To compare the therapeutic effectiveness of daily exposure to narrowband (NB) UV-B vs broadband (BB) UV-B with and without tar.Half-body exposures to NB UV-B or BB UV-B were given daily for 4 weeks in this comparative treatment study. Narrowband UV-B
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::50c034f4be1f744dd604bdd67381f2f3
https://pubmed.ncbi.nlm.nih.gov/9420549
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9
Expression of cellular-yes protein in mammalian tissues
Autor: Y H, Zhao, J G, Krueger, M, Sudol
Publikováno v: Oncogene. 5(11)
Expression of the c-yes proto-oncogene in normal mammalian tissues was studied by immunohistochemistry and by immunoprecipitation assays using affinity purified anti-yes IgG. The antibody was raised against the amino-terminal domain of the human c-ye
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1711f451ecd7865b3b7d0232115eb357
https://pubmed.ncbi.nlm.nih.gov/2267131
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