Zobrazeno 1 - 10
of 22
pro vyhledávání: '"J G, Granneman"'
Autor:
J G Granneman
The recent demonstration of active brown adipose tissue (BAT) in adult humans, along with the discovery of vast cellular and metabolic plasticity of adipocyte phenotypes, has given new hope of targeting adipose tissue for therapeutic benefit. Applica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd00e8d93d07665ba2573d036e22cee4
https://europepmc.org/articles/PMC4850572/
https://europepmc.org/articles/PMC4850572/
Publikováno v:
Glia. 33(3)
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors of the nuclear hormone receptor superfamily that have been described as master genes that switch cells from an undifferentiated phenotype to a differentiat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e175f811fc34e6df2cc8cea8dda7c5c
https://pubmed.ncbi.nlm.nih.gov/11241737
https://pubmed.ncbi.nlm.nih.gov/11241737
Publikováno v:
Journal of neurochemistry. 76(5)
The importance of the nuclear receptor nurr1 for the appropriate development of mesencephalic dopamine-synthesizing neurons has been clearly demonstrated through the targeted disruption of the nurr1 gene. The persistence of nurr1 expression in adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a983517d1d18d3ee2f81fcae652fbfd
https://pubmed.ncbi.nlm.nih.gov/11238740
https://pubmed.ncbi.nlm.nih.gov/11238740
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 294(3)
Pharmacological responses to aryloxypropanolamines were examined in cells expressing rat or human beta(1)-adrenergic receptors (ARs) using adenylyl cyclase assays. The aryloxypropanolamines CGP 12177 and LY 362884, originally developed as beta(3)-AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d96a51683f47e53f5bc7ad07823969c
https://pubmed.ncbi.nlm.nih.gov/10945842
https://pubmed.ncbi.nlm.nih.gov/10945842
Publikováno v:
Molecular pharmacology. 57(2)
CGP 12177 is a beta-adrenergic receptor (AR) ligand that has been used to characterize the beta3-AR and the putative beta4-AR. The ability of CGP 12177 to activate beta1-AR when overexpressed in vitro and the presence of beta1-AR in tissues expressin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c50dcdb67ba92a6a6a2ea96132e3a9bb
https://pubmed.ncbi.nlm.nih.gov/10648634
https://pubmed.ncbi.nlm.nih.gov/10648634
Autor:
J. G. Granneman
Publikováno v:
Obesity: Pathology and Therapy ISBN: 9783642640704
The physiological actions of catecholamines are mediated via a- and β-adrenergic receptors (AR). Activation of adipocyte βAR results in lipid mobilization and release from white adipose tissue, and oxidation of fatty acids in brown fat. The net eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb65ece16f5889b2cdb0b198d09a3689
https://doi.org/10.1007/978-3-642-59651-3_14
https://doi.org/10.1007/978-3-642-59651-3_14
Autor:
J G, Granneman, Y, Zhai, Z, Zhu, M J, Bannon, S A, Burchett, C J, Schmidt, R, Andrade, J, Cooper
Publikováno v:
Molecular pharmacology. 54(4)
A novel splice variant of RGS 9 was isolated from a rat hypothalamus, human retina, and a human kidney (Wilm's) tumor. This variant, termed RGS 9L, differs from the retinal form (termed RGS 9S) identified previously in that it contains a 211- (rat) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8aa3f29e8f95837ef055a9bc4dc797d2
https://pubmed.ncbi.nlm.nih.gov/9765512
https://pubmed.ncbi.nlm.nih.gov/9765512
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(1)
The rat gastric fundus is known to possess an "atypical" beta-adrenergic receptor that mediates relaxation to isoproterenol. The purpose of this study was to characterize the relationship between this "atypical" beta receptor in the rat stomach and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af6620f8858400ca613003e7b01e8edf
https://pubmed.ncbi.nlm.nih.gov/7815362
https://pubmed.ncbi.nlm.nih.gov/7815362
Autor:
A, Chaudhry, J G, Granneman
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(3)
Previous studies have suggested that the beta 3 receptor fails to become desensitized following acute agonist exposure. We have determined whether this resistance to desensitization is an intrinsic property of the human beta 3 receptor by examining b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09d542308b94c7c08a04f7b188e151f1
https://pubmed.ncbi.nlm.nih.gov/7996434
https://pubmed.ncbi.nlm.nih.gov/7996434
Publikováno v:
Molecular pharmacology. 44(2)
Comparison of the rodent and human beta 3-adrenergic receptor cDNAs with the respective genomic sequences has revealed unexpectedly that these genes contain two protein-coding exons. The rat gene was cloned recently and was found to contain three exo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59bc4f320a67315f3d14cfe5d3a91db9
https://pubmed.ncbi.nlm.nih.gov/8102781
https://pubmed.ncbi.nlm.nih.gov/8102781