Zobrazeno 1 - 10
of 15
pro vyhledávání: '"J G, Flannery"'
Publikováno v:
Investigative ophthalmologyvisual science. 41(13)
We previously demonstrated that 350 bp of the human rod cGMP phosphodiesterase beta-subunit (beta-PDE) gene promoter are sufficient to direct high levels of gene expression in human Y-79 retinoblastoma cells in vitro. In this study the cell specifici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c61453525fab631f3e4416ef99946018
https://pubmed.ncbi.nlm.nih.gov/11095595
https://pubmed.ncbi.nlm.nih.gov/11095595
Publikováno v:
Investigative ophthalmologyvisual science. 41(11)
We evaluated adeno-associated virus (AAV)-mediated gene transfer of basic fibroblast growth factor (FGF-2) as a therapy for photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa.Recombinant adeno-associated virus vector (rAAV)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::703e042969bc1dcc3e205b35af2de2b7
https://pubmed.ncbi.nlm.nih.gov/11006261
https://pubmed.ncbi.nlm.nih.gov/11006261
Publikováno v:
Investigative ophthalmologyvisual science. 41(6)
To determine the extent to which rhodopsin mis-sorting and constitutive activation of the phototransduction cascade contribute to retinal degeneration in a transgenic rat model of retinitis pigmentosa.Retinas from transgenic rats expressing truncated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e31b84a8dc365fcc97b5cf03d5d46ea
https://pubmed.ncbi.nlm.nih.gov/10798675
https://pubmed.ncbi.nlm.nih.gov/10798675
Publikováno v:
Investigative ophthalmologyvisual science. 31(2)
We have examined eyes from a heterozygote (carrier) of choroideremia, an X-linked disease. Gross examination revealed irregular pigmentation at the level of the retinal pigment epithelium (RPE) except at the posterior pole, and islands of well define
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b777510d2bc2d9285ed585447f44630b
https://pubmed.ncbi.nlm.nih.gov/2303326
https://pubmed.ncbi.nlm.nih.gov/2303326
Autor:
J G, Flannery
Publikováno v:
Psychotherapy and psychosomatics. 30(3-4)
Unexplained physical distress, when associated with alexithymia, becomes a diagnostic puzzle leading to prolonged investigation, ineffective treatment, and psychiatric referral. The persistent, often almost indescribable quality of the distress sugge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1b7c62f43a28ef58b7dab4c9c0b6d92
https://pubmed.ncbi.nlm.nih.gov/740847
https://pubmed.ncbi.nlm.nih.gov/740847
Publikováno v:
Investigative ophthalmologyvisual science. 27(7)
The retinal pigment epithelium (RPE) is responsible for transport of retinol from the choroidal circulation to the photoreceptors. In the intact eye, this process is mediated by membrane receptors for plasma retinol binding protein (RBP) distributed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::747d3e9b04a264135213dfa1c5ad9f30
https://pubmed.ncbi.nlm.nih.gov/3013795
https://pubmed.ncbi.nlm.nih.gov/3013795
Autor:
J G, Flannery, S K, Fisher
Publikováno v:
Investigative ophthalmologyvisual science. 25(2)
To further examine the endogenous rhythm of disc shedding and phagocytosis observed in several species, adult Xenopus were entrained to a 12 hr light/12 hr dark cycle and then placed in constant darkness. At various times during a 3-day period of con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b87d94c292b03994a80b9fe3fd63bcca
https://pubmed.ncbi.nlm.nih.gov/6321387
https://pubmed.ncbi.nlm.nih.gov/6321387
Publikováno v:
Investigative ophthalmologyvisual science. 30(2)
The eyes of a 17-year-old male donor who was affected with autosomal dominant retinitis pigmentosa with variable expressivity have recently become available for study. Initial macroscopic examination of the fundus revealed bone spicules located in 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8c538fed5a51b9f1745146373cbeb6d
https://pubmed.ncbi.nlm.nih.gov/2914751
https://pubmed.ncbi.nlm.nih.gov/2914751
Publikováno v:
Investigative ophthalmologyvisual science. 29(7)
Quantitative electron microscope immunocytochemistry, employing an antibody specific to opsin, was used to evaluate the amount and location of opsin in Rana pipiens rod photoreceptors throughout a 24 hr light/dark cycle. We found a distinct diurnal r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::700a2981f0ef765271321d08c3c88fb6
https://pubmed.ncbi.nlm.nih.gov/2971023
https://pubmed.ncbi.nlm.nih.gov/2971023
Publikováno v:
Investigative ophthalmologyvisual science. 26(11)
The concentration of cGMP, cAMP, protein and the number of cone and rod photoreceptors have been measured in parallel arrays of punches, 3 mm in diameter, taken from each quadrant of normal human retinas. A separate punch containing the fovea and par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::435abb809c5a865f7f841119c9e5b9df
https://pubmed.ncbi.nlm.nih.gov/2997074
https://pubmed.ncbi.nlm.nih.gov/2997074