Zobrazeno 1 - 10
of 27
pro vyhledávání: '"J G, Culvenor"'
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 81, Pp 63-68 (1986)
Externí odkaz:
https://doaj.org/article/f2c74b35d6e54023b11572eed41b0a03
Publikováno v:
Molecular and Biochemical Parasitology. 62:263-270
In order to study antigens from the rodent malaria Plasmodium chabaudi, clones reacting with mouse hyperimmune serum were selected from an expression library of blood-stage P. chabaudi cDNAs in the vector pGEX-2T. Sixty-four such clones were shown to
Publikováno v:
The Journal of Cell Biology
Resistance to chloroquine in Plasmodium falciparum bears a striking similarity to the multi-drug resistance (MDR) phenotype of mammalian tumor cells which is mediated by overexpression of P-glycoprotein. We show here that the P. falciparum homologue
Autor:
J. G. Culvenor, P E Crewther
Publikováno v:
The Journal of Protozoology. 37:59-65
Localization of the S-antigen of Plasmodium falciparum isolate FCQ27/PNG, from Papua New Guinea, was studied by post-embedding immunoelectron microscopy using affinity-purified rabbit antibodies raised against the repeat region of the antigen. Labell
Autor:
B C, Campbell, C A, McLean, J G, Culvenor, W P, Gai, P C, Blumbergs, P, Jäkälä, K, Beyreuther, C L, Masters, Q X, Li
Publikováno v:
Journal of neurochemistry. 76(1)
Intracellular inclusions containing alpha-synuclein (alpha SN) are pathognomonic features of several neurodegenerative disorders. Inclusions occur in oligodendrocytes in multiple system atrophy (MSA) and in neurons in dementia with Lewy bodies (DLB)
Autor:
G, Evin, D, Le Brocque, J G, Culvenor, D, Galatis, A, Weidemann, K, Beyreuther, C L, Masters, R, Cappai
Publikováno v:
Neuroreport. 11(2)
Presenilin (PS) mutations are associated with early-onset Alzheimer's disease and PS proteins are involved with gamma-secretase cleavage of the amyloid precursor protein, APP. We have shown previously that alpha-, beta- and gamma-secretase cleavages
Publikováno v:
Journal of neurochemistry. 73(5)
Immunohistochemical studies have shown that oligodendroglial inclusions in multiple system atrophy contain alpha-synuclein, a synaptic protein also found in Lewy bodies in Parkinson's disease. We have now used density gradient enrichment and an anti-
Autor:
J G, Culvenor, F, Maher, G, Evin, F, Malchiodi-Albedi, R, Cappai, J R, Underwood, J B, Davis, E H, Karran, G W, Roberts, K, Beyreuther, C L, Masters
Publikováno v:
Journal of neuroscience research. 49(6)
The recently identified Alzheimer's disease-associated presenilin 1 and 2 (PS1 and PS2) genes encode two homologous multi membrane-spanning proteins. Rabbit antibodies to the N-terminal domain of PS1 detected PS1 in human neuroblastoma SH-SY5Y wild t
Autor:
Karen Holmberg, Janette Allison, Raphael K. Bartholomeusz, Leonie Malcolm, J. G. Culvenor, Jacques F. A. P. Miller
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 88(6)
Overexpression of heavy chains of the class I major histocompatibility complex in islet beta cells of transgenic mice is known to induce nonimmune diabetes. We have now overexpressed the secretory protein beta 2-microglobulin in beta cells. Transgeni
Electron microscopy was used to study the fate of Plasmodium falciparum ring-infected erythrocyte surface antigen after merozoite invasion by using postembedding immunolabeling. The antigen was localized to small dense granules located centrally or l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b9c6688ab043c3b7d3c0840481d1244
https://europepmc.org/articles/PMC258387/
https://europepmc.org/articles/PMC258387/