Zobrazeno 1 - 10
of 123
pro vyhledávání: '"J Francis Borgio"'
Autor:
Sayed Abdulazeez, Shaheen Sultana, Noor B Almandil, Dana Almohazey, B Jesvin Bency, J Francis Borgio
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212492 (2019)
BackgroundB-cell lymphoma/leukaemia 11A (BCL11A) is a C2H2-type zinc-finger transcription factor protein that is a critical modulator of haemoglobin switching and suppresses the production of foetal haemoglobin. Variation in the BCL11A gene ameliorat
Externí odkaz:
https://doaj.org/article/547f44d35bec4d9da244f44972e1c23b
Autor:
J Francis Borgio
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185270 (2017)
Recent studies on the variants in duplicated human alpha globin genes (HBA2 and HBA1) actively target the α-globin gene as molecular modulators for the treatment of β-thalassemia major. Identification of the exact position of variant in HBA1, HBA2
Externí odkaz:
https://doaj.org/article/4b9fd9ae139a498cb56b91d2f8009bba
Autor:
Sayed AbdulAzeez, J Francis Borgio
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147702 (2016)
BACKGROUND:α-Thalassemia (α-thal) is a genetic disorder caused by the substitution of single amino acid or large deletions in the HBA1 and/or HBA2 genes. METHOD:Using modern bioinformatics tools as a systematic in-silico approach to predict the del
Externí odkaz:
https://doaj.org/article/9b20cf8d0f2741b19eb3c588de46c8ea
Autor:
Reem AlJindan, Nehal Mahmoud, Doaa M. AlEraky, Noor B. Almandil, Sayed AbdulAzeez, J. Francis Borgio
Publikováno v:
Journal of Infection and Public Health, Vol 17, Iss 7, Pp 102463- (2024)
Background: Enterococcus avium (E. avium) is a Gram-positive nosocomial pathogen that is commonly isolated from the alimentary tract. The objective of this functional genomics study was to identify the resistant genes by analyzing the genome of E. av
Externí odkaz:
https://doaj.org/article/3bc2e332d33641989ae5d34b757dc18d
Autor:
J. Francis Borgio, Noor B. Almandil, Prathas Selvaraj, J. Sherlin John, Rahaf Alquwaie, Eman AlHasani, Norah F. Alhur, Razan Aldahhan, Reem AlJindan, Dana Almohazey, Sarah Almofty, T. Stalin Dhas, Sayed AbdulAzeez
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 810 (2024)
Novel antifungal drugs are urgently needed to treat candidiasis caused by the emerging fungal multidrug-resistant pathogen Candida auris. In this study, the most cost-effective drug repurposing technology was adopted to identify an appropriate option
Externí odkaz:
https://doaj.org/article/aee7424bd5ac448bb78064087e200edc
Entomopathogenic fungi and their biological control of Tetranychus urticae: Two-spotted spider mites
Autor:
Jawaher Khamis Al-Zahrani, Amira Hassan Al-Abdalall, Mohamed Aly Osman, Lena A. Aldakheel, Nada Faisal AlAhmady, Sumayh A. Aldakeel, Sayed AbdulAzeez, J. Francis Borgio, Medhat A. ElNaggar, Nadiyah M. Alabdallah, Mona M. Almustafa
Publikováno v:
Journal of King Saud University: Science, Vol 35, Iss 8, Pp 102910- (2023)
The two-spotted spider mite (TSSM) Tetranychus urticae, is regarded as one of the most dangerous pests responsible for great losses in most of agricultural crops. It is a persistent pest in Saudi Arabia, especially in greenhouses where T. urticae is
Externí odkaz:
https://doaj.org/article/7116e6667ac2462981b6c83ff8318920
Autor:
J. Francis Borgio, Rahaf Alhujaily, Rahaf Alquwaie, Maryam Jawad Alabdullah, Eman AlHasani, Wojod Alothman, Rawan Khalid Alaqeel, Aqeelah Salman Alfaraj, Ayidah Kaabi, Norah F. Alhur, Sultan Akhtar, Reem AlJindan, Sarah Almofty, Noor B. Almandil, Sayed AbdulAzeez
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4261-4276 (2023)
There is a global health concern associated with the emergence of the multidrug-resistant (MDR) fungus Candida auris, which has significant mortality rates. Finding innovative and distinctive anti-Candida compounds is essential for treating infection
Externí odkaz:
https://doaj.org/article/b28bd5f4c54e42b3af772c1f6a9f80f9
Autor:
J. Francis Borgio, Reem AlJindan, Lujeen H. Alghourab, Rahaf Alquwaie, Razan Aldahhan, Norah F. Alhur, Doaa M. AlEraky, Nehal Mahmoud, Noor B. Almandil, Sayed AbdulAzeez
Publikováno v:
Biology, Vol 12, Iss 10, p 1296 (2023)
We report on a highly virulent, multidrug-resistant strain of Enterococcus faecalis IRMC827A that was found colonizing a long-term male patient at a tertiary hospital in Khobar, Saudi Arabia. The E. faecalis IRMC827A strain carries several antimicrob
Externí odkaz:
https://doaj.org/article/09b05e2af48643469ee6a16ce13012ee
Autor:
Noor B. Almandil, Maram Adnan Alismail, Hind Saleh Alsuwat, Abdulla AlSulaiman, Sayed AbdulAzeez, J. Francis Borgio
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundAutism Spectrum Disorder (ASD) is a multifactorial, neurodevelopmental disorder, characterized by deficits in communication, restricted and repetitive behaviors. ASD is highly heritable in Saudi Arabia; indecencies of affected individuals a
Externí odkaz:
https://doaj.org/article/febc026395e644548a9f658c96b0bded
Autor:
J. Francis Borgio
Publikováno v:
Archives of Medical Science, Vol 19, Iss 3, Pp 765-783 (2021)
More than 25 million DNA variations have been discovered as novel including major alleles from the Arab population. Exome studies on the Saudi genome discovered > 3000 novel nucleotide variants associated with > 1200 rare genetic disorders. Reclassif
Externí odkaz:
https://doaj.org/article/12b7f0225aa941a4ad285440822894a1