Zobrazeno 1 - 10
of 75
pro vyhledávání: '"J Forgo"'
Publikováno v:
Journal of the American Society of Nephrology. 11:1961-1968
Parathyroid hormone (PTH)-induced inhibition of renal proximal tubular Na/P(i) cotransport involves two consecutive steps: endocytosis followed by lysosomal degradation of the type IIa Na/P(i) cotransporter. Tyrosine-, dileucine-, and diacidic-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d024964ace71eb6fbcfd28a0953b3e3
https://doi.org/10.1681/asn.v11111961
https://doi.org/10.1681/asn.v11111961
Autor:
Nati Hernando, Heini Murer, Zoubida Karim-Jimenez, H. Galliker, J Forgo, Jürg Biber, S. Sheikh
Publikováno v:
American Journal of Physiology-Renal Physiology. 278:F361-F368
Targeting of newly synthesized transporters to either the apical or basolateral domains of polarized cells is crucial for the function of epithelia, such as in the renal proximal tubule or in the small intestine. Recently, different sodium-phosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6846fc8377b6039a413443b93aedccdc
https://doi.org/10.1152/ajprenal.2000.278.3.f361
https://doi.org/10.1152/ajprenal.2000.278.3.f361
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 438:392-396
The importance of phosphatidylinositide 3- kinase(s) [PI 3-kinase(s)] in membrane trafficking processes led us to examine its/their possible role in parathyroid-hormone- (PTH-) induced endocytosis and lysosomal degradation of the type IIa Na/Pi-cotra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7210c0bdd2dbfeeb06583cbae95066
https://doi.org/10.1007/s004240050926
https://doi.org/10.1007/s004240050926
Publikováno v:
American Journal of Physiology-Renal Physiology. 276:F720-F725
Parathyroid hormone (PTH) leads to the inhibition of Na-Picotransport activity and to the downregulation of the number of type II Na-Picotransporters in proximal tubules, as well as in opossum kidney (OK) cells. PTH is known also to lead to an activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b7caeb60c5cb1a15188bd0cccd0579
https://doi.org/10.1152/ajprenal.1999.276.5.f720
https://doi.org/10.1152/ajprenal.1999.276.5.f720
Autor:
Chung Ming Tse, Heini Murer, Corinna Helmle-Kolb, F. Di Sole, J Forgo, Helene Hilfiker, Valeria Casavola, Mark Donowitz
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 434:123-131
NHE3 is most likely the isoform involved in renal reabsorption of HCO3- and Na+. The functional properties of the "cloned" NHE3 isoform, including its transport regulation by extra- and intracellular stimuli, have so far been studied using non-epithe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de415ddcced60bb1dcad3957be1caa85
https://doi.org/10.1007/s004240050372
https://doi.org/10.1007/s004240050372
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 430:636-644
Parathyroid hormone (PTH) inhibits renal proximal tubular phosphate (Pi) and bicarbonate reabsorption by regulating the activity of apical Na/Pi cotransport and Na/H exchange. Two renal epithelial cell lines ["proximal tubular", LLC-PK1; "distal tubu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69022eb5aeb67172973f9252c8aa850e
https://doi.org/10.1007/bf00386157
https://doi.org/10.1007/bf00386157
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 422:516-522
The role of microtubules and actin microfilaments in adaptive changes of the apical Na-dependent transport of phosphate (Pi) was investigated in opossum kidney (OK) cells. Up-regulation of Na/Pi cotransport was achieved by incubating OK cells in a me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a476c0ba8059d9ed1a8ce2fa3a0b4954
https://doi.org/10.1007/bf00375080
https://doi.org/10.1007/bf00375080
Publikováno v:
Kidney and Blood Pressure Research. 16:93-104
An SV-40-transformed cell line of rabbit S2 proximal tubular origin (RKPC-2 cells) was used to characterize Na/Pi cotransport. Pi saturation experiments showed simple Michaelis-Menten behaviour and an apparent Km of 106 µM; Hill analysis of Na+ conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f922bb87ff2f7b5ef38cd580fb0839a8
https://doi.org/10.1159/000173755
https://doi.org/10.1159/000173755
Publikováno v:
Europe PubMed Central
As a first step within an experimental strategy (expression cloning) leading to the structural identification of the two brush-border membrane transport systems for phosphate and sulfate, we have studied the expression of Na(+)-dependent uptake of ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4075f93e7554a1b6153dcb27eb881d
https://doi.org/10.1016/s0021-9258(19)38350-4
https://doi.org/10.1016/s0021-9258(19)38350-4
Autor:
C, Mora, J, Chillarón, M J, Calonge, J, Forgo, X, Testar, V, Nunes, H, Murer, A, Zorzano, M, Palacín
Publikováno v:
The Journal of biological chemistry. 271(18)
Several studies have shown that the cRNA of human, rabbit, or rat rBAT induces in Xenopus oocytes sodium-independent, high affinity uptake of L-cystine via a system b0,(+)-like amino acid exchanger. We have shown that mutations in rBAT cause type I c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9a493e646f43140cac21c452ff252a6
https://pubmed.ncbi.nlm.nih.gov/8631857
https://pubmed.ncbi.nlm.nih.gov/8631857