Zobrazeno 1 - 10
of 1 836
pro vyhledávání: '"J Faure"'
Autor:
Alexandra M. Bendel, Andre J. Faure, Dominique Klein, Kenji Shimada, Romane Lyautey, Nicole Schiffelholz, Georg Kempf, Simone Cavadini, Ben Lehner, Guillaume Diss
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The encoding and evolution of specificity and affinity in protein-protein interactions is poorly understood. Here, we address this question by quantifying how all mutations in one protein, JUN, alter binding to all other members of a protein
Externí odkaz:
https://doaj.org/article/94b0ef1f5243491094d86a12969bca01
Publikováno v:
Geoscientific Model Development, Vol 16, Pp 7339-7355 (2023)
A key challenge in paleoseismology is constraining the timing and occurrence of past earthquakes to create an earthquake history along faults that can be used for testing or building fault-based seismic hazard assessments. We present a new methodolog
Externí odkaz:
https://doaj.org/article/a3adc0e9a9414c9cb0eb2f829967c70d
Autor:
J. Monzac, S. Smartsev, J. Huijts, L. Rovige, I. A. Andriyash, A. Vernier, V. Tomkus, V. Girdauskas, G. Raciukaitis, M. Mackevičiūtė, V. Stankevic, A. Cavagna, J. Kaur, A. Kalouguine, R. Lopez-Martens, J. Faure
Publikováno v:
Physical Review Research, Vol 6, Iss 4, p 043099 (2024)
We present significant advances in laser wakefield acceleration (LWFA) operating at a 1 kHz repetition rate, employing a sub-TW, few-femtosecond laser and a continuously flowing hydrogen gas target. We conducted a comprehensive study assessing how th
Externí odkaz:
https://doaj.org/article/1e71899621cf4301bf08ef95e209d988
Publikováno v:
New Journal of Physics, Vol 16, Iss 2, p 023023 (2014)
Using particle-in-cell simulations, we study the interaction of few-mJ–few-cycle laser pulses with an underdense plasma at resonant density. In this previously unexplored regime, it is found that group velocity dispersion is a key ingredient of the
Externí odkaz:
https://doaj.org/article/1230ad3241754030905ff154b06754bd
Publikováno v:
New Journal of Physics, Vol 15, Iss 5, p 053016 (2013)
We report on an experimental demonstration of laser wakefield electron acceleration using a sub-TW power laser by tightly focusing 30 fs laser pulses with an 8 mJ pulse energy on a 100 μ m scale gas target. The experiments are carried out at an unpr
Externí odkaz:
https://doaj.org/article/f81fe24e81e14a6d9450ec12d1f7d1d1
Autor:
Meschis, M., Roberts, G.P., Robertson, J., Mildon, Z.K., Sahy, D., Goswami, R., Sgambato, C., Walker, J. Faure, Michetti, A.M., Iezzi, F.
Publikováno v:
In Geomorphology 1 November 2022 416
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-23 (2020)
Abstract Deep mutational scanning (DMS) enables multiplexed measurement of the effects of thousands of variants of proteins, RNAs, and regulatory elements. Here, we present a customizable pipeline, DiMSum, that represents an end-to-end solution for o
Externí odkaz:
https://doaj.org/article/00c2de803bfe4d1cb9a45d70315f62d2
Autor:
I. Gonzalez-Vallejo, V. L. R. Jacques, D. Boschetto, G. Rizza, A. Hadj-Azzem, J. Faure, D. Le Bolloc'h
Publikováno v:
Structural Dynamics, Vol 9, Iss 1, Pp 014502-014502-9 (2022)
We use ultrafast electron diffraction to study the out-of-equilibrium dynamics of the charge density wave (CDW) phase transition in GdTe3, a quasi-two-dimensional compound displaying a unidirectional CDW state. Experiments were conducted at different
Externí odkaz:
https://doaj.org/article/5799e00da5444d24bf9c4ea542a5e8c6
Autor:
Benedetta Bolognesi, Andre J. Faure, Mireia Seuma, Jörn M. Schmiedel, Gian Gaetano Tartaglia, Ben Lehner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
TDP43 aggregates are a hallmark of amyotrophic lateral sclerosis. By using deep mutagenesis to measure the toxicity of more than 50,000 mutations in the prion domain of TDP43, the authors conclude that mutations that increase toxicity promote formati
Externí odkaz:
https://doaj.org/article/0fca2a044c88458bacfb8b409c6af5b7
Publikováno v:
eLife, Vol 10 (2021)
Plaques of the amyloid beta (Aß) peptide are a pathological hallmark of Alzheimer’s disease (AD), the most common form of dementia. Mutations in Aß also cause familial forms of AD (fAD). Here, we use deep mutational scanning to quantify the effec
Externí odkaz:
https://doaj.org/article/70aa61e788c243829de236a89dae4fc6