Zobrazeno 1 - 10 of 12 pro vyhledávání: '"J F Glover"'
1
Evaluation of two carrier protein-angiotensin I conjugate vaccines to assess their future potential to control high blood pressure (hypertension) in man
Autor: H L Sharp, J P Richards, J F Glover, Timothy Mant, L Sjostrom, Terence Bennett, Alan Rushton, M R Downham, A Rosul, Sheila M. Gardiner, T R Auton
Publikováno v: British Journal of Clinical Pharmacology. 56:505-512
Aims We aim to modulate the renin–angiotensin system (RAS) by active immunization against angiotensin I hormone (AI), potentially providing a novel conjugate vaccine treatment for hypertension in man. Methods Immunization studies in rat and human s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e030243087d11c9927bbf54c600563f1
https://doi.org/10.1046/j.1365-2125.2003.01926.x
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2
Active immunization with angiotensin I peptide analogue vaccines selectively reduces the pressor effects of exogenous angiotensin I in conscious rats
Autor: Phillip John Morgan, Terence Bennett, M R Downham, H L Sharp, T R Auton, J F Glover, Harry Martin, Alan Rushton, Julie E. March, P.A. Kemp, Sheila M. Gardiner
Publikováno v: British Journal of Pharmacology. 129:1178-1182
Male, Sprague-Dawley rats were actively immunized with novel angiotensin vaccines, and their pressor responses to exogenous angiotensin I (AI) and angiotensin II (AII) were assessed in vivo. Serum antibody titres were also measured. The most effectiv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7d4603f08ccfdce58a3fbe8a57f1610
https://doi.org/10.1038/sj.bjp.0703178
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3
Evaluation of two carrier protein-angiotensin I conjugate vaccines to assess their future potential to control high blood pressure (hypertension) in man
Autor: M R, Downham, T R, Auton, A, Rosul, H L, Sharp, L, Sjöström, A, Rushton, J P, Richards, T G K, Mant, S M, Gardiner, T, Bennett, J F, Glover
Publikováno v: British journal of clinical pharmacology. 56(5)
We aim to modulate the renin-angiotensin system (RAS) by active immunization against angiotensin I hormone (AI), potentially providing a novel conjugate vaccine treatment for hypertension in man.Immunization studies in rat and human subjects compare
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::915725f8b1e4042dfb2aeeac8ada08e4
https://pubmed.ncbi.nlm.nih.gov/14651724
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4
Active immunization with angiotensin I peptide analogue vaccines selectively reduces the pressor effects of exogenous angiotensin I in conscious rats
Autor: S M, Gardiner, T R, Auton, M R, Downham, H L, Sharp, P A, Kemp, J E, March, H, Martin, P J, Morgan, A, Rushton, T, Bennett, J F, Glover
Publikováno v: British journal of pharmacology. 129(6)
1. Male, Sprague-Dawley rats were actively immunized with novel angiotensin vaccines, and their pressor responses to exogenous angiotensin I (AI) and angiotensin II (AII) were assessed in vivo. Serum antibody titres were also measured. 2. The most ef
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1a96c0d0e48a270ba4ac7ef1f9d60ab6
https://pubmed.ncbi.nlm.nih.gov/10725266
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6
Dimethyl Sulphoxide (DMSO) Disassembles Tobacco Mosaic Virus Predominantly from the 5'-end of the Viral RNA
Autor: J. F. Glover, T. M. A. Wilson, G. P. Lomonossoff
Publikováno v: Journal of General Virology. 53:225-234
Summary The effect of dimethyl sulphoxide (DMSO) on the stability of native and EDTA-treated tobacco mosaic virus (TMV, Vulgare strain) has been reinvestigated using a variety of chemical and biochemical techniques. Contrary to earlier reports, we co
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56539bf220f6acabba93ce671e05c22c
https://doi.org/10.1099/0022-1317-53-2-225
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9
Interaction of phenol red with estrogenic and antiestrogenic action on growth of human breast cancer cells ZR-75-1 and T-47-D
Autor: J F, Glover, J T, Irwin, P D, Darbre
Publikováno v: Cancer research. 48(13)
Studies reported here confirm that the pH indicator, phenol red, acts as a weak estrogen and reexamine the significance of estrogenic and antiestrogenic effects on growth of the human breast cancer cell lines ZR-75-1 and T-47-D in the absence of phen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6a256946a0dc7ff4f766394f181a6d66
https://pubmed.ncbi.nlm.nih.gov/3378212
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10
Culture shock. Synthesis of heat-shock-like proteins in fresh primary cell cultures
Autor: A P, Wolffe, J F, Glover, J R, Tata
Publikováno v: Experimental cell research. 154(2)
The isolation of Xenopus liver, lung and testis cells by collagenase digestion of the tissue, followed by Percoll density gradient centrifugation, was characterized by the preferential synthesis of two proteins whose size and charge were similar to 7
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0ece36162f54516f8b38134de4ac63df
https://pubmed.ncbi.nlm.nih.gov/6541149
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