Zobrazeno 1 - 10 of 11 pro vyhledávání: '"J F, Siuda"'
1
Synthesis, antiinflammatory, and cytotoxic activities of 2-alkyl and 2-benzyl-2-dimethylaminomethyl-5-(E)-arylidene cyclopentanone hydrochlorides
Autor: H, Chen, Z, Ji, L K, Wong, J F, Siuda, V L, Narayanan
Publikováno v: Pharmaceutical research. 13(10)
A series of 2-substituted-2-dimethylaminomethyl-5-(E)-arylidene cyclopentanones, 4 were synthesized. The main objective of this investigation was to explore the structural parameters necessary for antiinflammatory activity in this series of compounds
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2383d73d7f7add254cb9a974bfd3e064
https://pubmed.ncbi.nlm.nih.gov/8899838
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2
Synthesis and cytotoxic activities of the amine-exchange products of 2-dimethylaminomethyl-5-(E)-substituted arylidene cyclopentanones with anilines: 2-arylaminomethyl-5-(E)-arylidene cyclopentanones
Autor: H, Chen, Z, Ji, L K, Wong, J F, Siuda, V L, Narayanan
Publikováno v: Drug design and discovery. 14(1)
A series of 2-arylaminomethyl, and 2-(4-morpholinylmethyl)-5-(E)-arylidene cyclopentanones have been synthesized via an amine-exchange reaction. Most of the compounds showed significant cytotoxic activities, in vitro, on various human cancer cell lin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::28499c9447874a08322ef12c82602e87
https://pubmed.ncbi.nlm.nih.gov/8854044
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