Zobrazeno 1 - 8
of 8
pro vyhledávání: '"J F, Sigurjónsdóttir"'
Autor:
J. F. Sigurjónsdóttir, S. D. Sigfússon, Hakon H. Sigurdsson, Einar Stefánsson, Már Másson, Thorsteinn Loftsson, Gudmundsdottir H
Publikováno v:
International Journal of Pharmaceutics. 212:29-40
The cyclodextrin solubilization of three benzodiazepines, i.e. alprazolam, midazolam and triazolam, was investigated. The cyclodextrin solubilization was enhanced through ring-opening of the benzodiazepine rings and ionization of the ring-open forms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b779f19f49d2e1f50891239925729332
https://doi.org/10.1016/s0378-5173(00)00580-9
https://doi.org/10.1016/s0378-5173(00)00580-9
Publikováno v:
International Journal of Pharmaceutics. 186:205-213
The influence of beta-cyclodextrin (betaCD), and various betaCD derivatives, on both the chemical and the physical stability of the polypeptide hormone salmon calcitonin (sCT) in aqueous solutions was investigated at elevated temperature (55 degrees
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5700a54a1250df9ffa3639002b6bf76f
https://doi.org/10.1016/s0378-5173(99)00183-0
https://doi.org/10.1016/s0378-5173(99)00183-0
Publikováno v:
Drug development and industrial pharmacy. 29(1)
Fluorine nuclear magnetic-resonance spectroscopy (19F-NMR) was used to measure complexation of three fluorine-containing drugs--dexamthasone, fluoxetine hydrochloride, and diflunisal sodium--with 2-hydroxypropyl-beta-cyclodextrin (HPbetaCD). Poor aqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbec613657abf05acef45b7092d091c1
https://pubmed.ncbi.nlm.nih.gov/12602498
https://pubmed.ncbi.nlm.nih.gov/12602498
Publikováno v:
Journal of pharmaceutical sciences. 91(11)
Phase‐solubility diagrams are frequently used to calculate stoichiometry of drug/cyclodextrin complexes. Linear diagrams (A L ‐type systems) are thought to indicate that the complexes are first order with respect to cyclodextrin and first or high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3635028e98e222361ec5b18759b266f
https://pubmed.ncbi.nlm.nih.gov/12379916
https://pubmed.ncbi.nlm.nih.gov/12379916
Publikováno v:
Die Pharmazie. 56(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3d2da80c9e4a09868fd7fb354d1c5b07
https://pubmed.ncbi.nlm.nih.gov/11594000
https://pubmed.ncbi.nlm.nih.gov/11594000
Autor:
E, Gudmundsdóttir, E, Stefánsson, G, Bjarnadóttir, J F, Sigurjónsdóttir, G, Gudmundsdóttir, M, Masson, T, Loftsson
Publikováno v:
Investigative ophthalmologyvisual science. 41(11)
To formulate aqueous eye drops containing methazolamide 1% in cyclodextrin solution and to evaluate their effect on intraocular pressure (IOP) in a double-blind randomized trial in humans. Methazolamide, a carbonic anhydrase inhibitor (CAI), has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::791ea68d22a532e299480bcf2c82b66e
https://pubmed.ncbi.nlm.nih.gov/11006251
https://pubmed.ncbi.nlm.nih.gov/11006251
Publikováno v:
Proceedings of the Ninth International Symposium on Cyclodextrins ISBN: 9789401059718
Calcitonin (CT) is a peptide hormone, discovered by Copp and colleagues in 1961. It is produced by the parafollicular cells of the thyroid gland in mammals and the ultimobranchial gland of birds and fish. It decreases blood calcium levels and inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52ea155d56dfc0ad843dc9a72bb54a25
https://doi.org/10.1007/978-94-011-4681-4_84
https://doi.org/10.1007/978-94-011-4681-4_84
Publikováno v:
Proceedings of the Ninth International Symposium on Cyclodextrins ISBN: 9789401059718
For various reasons, including drug availability, formulation bulk and toxicological considerations, it is important to use as little cyclodextrin (CD) as possible in pharmaceutical formulations. The complexation efficacy of CDs is generally rather l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a426d10e8643824b2475d3da069eaa04
https://doi.org/10.1007/978-94-011-4681-4_59
https://doi.org/10.1007/978-94-011-4681-4_59