Zobrazeno 1 - 10
of 52
pro vyhledávání: '"J F, Park"'
Autor:
G.E. Dagle, Richard E. Weller, J. F. Park, Daniel J. Strom, Charles R. Watson, R. L. Buschbom
Publikováno v:
Radiation Research. 178:447-467
Seven groups of 8-24 Beagle dogs, exposed to (239)PuO(2) aerosols by inhalation [mean initial lung depositions (ILD) of 0.0, 0.14, 0.63, 3.2, 13, 44 and 210 kBq] were observed throughout their lives to determine tissues at risk and dose-effect relati
Publikováno v:
Bulletin of the American Society of Veterinary Clinical Pathologists. 5:32-39
Autor:
J F, PARK, W J, CLARKE
Publikováno v:
HW-SA [reports]. U.S. Atomic Energy Commission. 86
Publikováno v:
HW-SA [reports]. U.S. Atomic Energy Commission. 103
Publikováno v:
International Journal of Radiation Biology. 68:63-70
Gross and light microscopic features of testicular neoplasms were examined in the male beagle dog used in three studies to examine the life-span effects of inhaled plutonium (Pu). One hundred and sixty-six cases of testicular neoplasia (TN) occurred
Autor:
E S, Gilbert, W C, Griffith, B B, Boecker, G E, Dagle, R A, Guilmette, F F, Hahn, B A, Muggenburg, J F, Park, C R, Watson
Publikováno v:
Radiation research. 150(1)
Combined analyses of data on 260 life-span beagle dogs that inhaled 238PuO2 at the Inhalation Toxicology Research Institute (ITRI) and at Pacific Northwest National Laboratory (PNNL) were conducted. The hazard functions (age-specific risks) for incid
Publikováno v:
Radiation research. 148(4)
Beagle dogs exposed to 238PuO2 aerosols (136 dogs, 13-22 per group, mean initial lung depositions of 0.0, 0.13, 0.68, 3.1, 13, 52 and 210 kBq) were observed throughout life to determine tissues at risk and dose-effect relationships. The pulmonary ret
Publikováno v:
Radiation research. 146(6)
Hypoadrenocorticism, known as Addison's disease in humans, was diagnosed in six beagles after inhalation of at least 1.7 kBq/g lung of 238PuO2. Histological examination of adrenal gland specimens obtained at necropsy revealed marked adrenal cortical
Publikováno v:
Radiation research. 144(1)
The effects of inhaled 238PuO2 deposited in the liver of dogs were studied in beagles exposed to initial lung depositions ranging from 5.7 to 2979.7 Bq/g lung. Approximately 20% of the initial lung deposition was translocated to the liver by 1500 day
Publikováno v:
Radiation research. 143(1)
A life-span study indicated that plutonium activity in the thoracic lymph nodes is a contributor to development of lymphopenia in beagles exposed to 239PuO2. Significant lymphopenia was found in 67 (58%) beagles given a single nose-only exposure to 2