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Diet-induced obesity alters anabolic signalling in mice at the onset of skeletal muscle regeneration

Autor: Nan Smith-Blair, Lemuel A. Brown, Nicholas P. Greene, Jacob L. Brown, David E. Lee, Tyrone A. Washington, J. F. Patton, Jamie Baum, Richard A. Perry

Publikováno v: Acta physiologica (Oxford, England). 215(1)

Aim Obesity is classified as a metabolic disorder that is associated with delayed muscle regeneration following damage. For optimal skeletal muscle regeneration, inflammation along with extracellular matrix remodelling and muscle growth must be tight

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd1a06b7c6b6599fdf65970c2992450
https://pubmed.ncbi.nlm.nih.gov/26052759

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Prolonged Intermittent Oral Topotecan in Patients with Refractory and/or Advanced Malignancies

Autor: John G. Kuhn, F. Anthony Greco, Sandra L. Greenwell, J. F. Patton, Howard A. Burris, Eric L. Raefsky, Dana S. Thompson, Margaret N. Baker, Charles E. McKay, John D. Hainsworth, Suzanne F. Jones

Publikováno v: American Journal of Cancer. 3:317-324

To determine the dose-limiting toxicity, maximum tolerated dose, and recommended phase II dosage of oral topotecan when administered in an intermittent schedule. Phase I study. Patients received a fixed dose of oral topotecan daily for 5 of 7 days fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::246ec7a984accf32df7e1343b396147b
https://doi.org/10.2165/00024669-200403050-00005

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Effects of a World Record Unsupported Ski Trek Across Greenland (The G2 Expedition) on Physical Performance and Body Composition

Autor: E. A. Harman, P. K. Opstad, J. F. Patton, P. N. Frykman, R. W. Hoyt

Prolonged exhaustive physical exertion is often predicted to result in reduced performance capacity ("overtraining"), through mechanisms of tissue breakdown and inadequate time for full recuperation. This is of importance in military operations, wher

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1e03089241461a5b746cb4e437b0237
https://doi.org/10.21236/ada396385

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Passive transfer, rate of decay, and protein specificity of antibodies against equine arteritis virus in horses from a Standardbred herd with high seroprevalence

Autor: P J, Hullinger, W D, Wilson, P V, Rossitto, J F, Patton, M C, Thurmond, N J, MacLachlan

Publikováno v: Journal of the American Veterinary Medical Association. 213(6)

To determine rate of decay of passively acquired antibodies in Standardbred foals on a farm with a high seroprevalence to equine arteritis virus (EAV) and to determine whether vertical or horizontal transmission of the virus was responsible for infec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c4a7c72dcc684ff2b88dbdd4769a5918
https://pubmed.ncbi.nlm.nih.gov/9743724

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Energy cost of wearing chemical protective clothing during progressive treadmill walking

Autor: J F, Patton, T E, Bidwell, M M, Murphy, R P, Mello, M E, Harp

Publikováno v: Aviation, space, and environmental medicine. 66(3)

While chemical protective (CP) clothing is known to adversely affect physical performance, few data exist regarding the physiological response of wearing US military CP clothing during incremental, dynamic exercise. To quantify the effects of CP clot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9ffafb9c8c031b3c66d5d8e810ba3da9
https://pubmed.ncbi.nlm.nih.gov/7661833

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Lower and upper body anaerobic performance in male and female adolescent athletes

Autor: B C, Nindl, M T, Mahar, E A, Harman, J F, Patton

Publikováno v: Medicine and science in sports and exercise. 27(2)

Little data exist for upper and lower body mechanical power capability of adolescent athletes. This study compared arm (A) and leg (L) anaerobic peak and mean power (PP and MP) of 20 male and 20 female adolescent athletes after normalization for body

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c2d6856566d159beb1f40b5d7b82af54
https://pubmed.ncbi.nlm.nih.gov/7564980

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Tracheoesophageal (TE) fistula development in a phase II trial of concurrent chemoradiation (CRT) and bevacizumab (B) in limited-stage small-cell lung cancer (LS-SCLC)

Autor: C. Farley, H. A. Burris, John D. Hainsworth, D. Blake, F. A. Greco, C. Meng, David R. Spigel, E. Raefsky, Lowell L. Hart, J. F. Patton

Publikováno v: Journal of Clinical Oncology. 26:7554-7554

7554 Background: TE fistulas are rare complications of thoracic and esophageal cancers and their treatments. We previously identified a TE fistula in 1 patient (pt) in a LS-SCLC trial (n=60) where ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::be9e7e2a6761cb6525dddb229e6664df
https://doi.org/10.1200/jco.2008.26.15_suppl.7554

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Phase II trial of irinotecan, carboplatin, and bevacizumab in patients with limited-stage small cell lung cancer

Autor: John D. Hainsworth, E. Vazquez, C. Farley, John D. Zubkus, J. F. Patton, Lowell L. Hart, David R. Spigel, F. A. Greco, D. A. Yardley, H. A. Burris

Publikováno v: Journal of Clinical Oncology. 25:18133-18133

18133 Background: In a previously reported phase II trial bevacizumab (B) was used as maintenance therapy following induction with irinotecan (I), carboplatin (C) and radiotherapy (RT) in patients (pts) with limited-stage small-cell lung cancer (LS-S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df70463dc77a95c1425405e7cc7e555c
https://doi.org/10.1200/jco.2007.25.18_suppl.18133

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A phase II trial of biweekly pemetrexed (P) and gemcitabine (G) in the first-line treatment (tx) of patients (pts) with advanced non-small cell lung cancer (NSCLC)

Autor: J. F. Patton, L. Simons, F. A. Greco, N. W. Peacock, J. H. Barton, Dianna Shipley, Denise A. Yardley, David R. Spigel, H. A. Burris, John D. Hainsworth

Publikováno v: Journal of Clinical Oncology. 24:17054-17054

17054 Background: P and G are active and well-tolerated non-platinum agents used in the tx of NSCLC. Previous trials have combined P and G in the first-line NSCLC setting using a 21D schedule. This trial examined the safety and activity of biweekly P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1550dfcab283b722d64f869f18a505e6
https://doi.org/10.1200/jco.2006.24.18_suppl.17054

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Preoperative oxaliplatin (O), docetaxel (D), capecitabine (C), and concurrent radiation therapy (RT) for patients (pts) with localized esophageal cancer: A phase I/II trial of the Minnie Pearl Cancer Research Network

Autor: J. F. Patton, C. Farley, F. A. Greco, Dianna Shipley, H. A. Burris, A. A. Meluch, John D. Hainsworth, Denise A. Yardley, David R. Spigel, Edward K. Barnes

Publikováno v: Journal of Clinical Oncology. 24:4058-4058

4058 Background: Preoperative chemoradiotherapy improves outcomes for pts with resectable esophageal cancer compared with surgery alone. We previously reported a 41% 3-year progression-free survival (PFS) with preoperative paclitaxel/carboplatin/5FU/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db4e6ef7278ccfb3862d7eb9e29802d2
https://doi.org/10.1200/jco.2006.24.18_suppl.4058

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