Zobrazeno 1 - 10
of 69
pro vyhledávání: '"J F, Nagelkerke"'
Autor:
Hein Putter, Elma Meershoek Klein-Kranenbarg, Peter J. K. Kuppen, Remco I.J.M. Aalbers, P. de Heer, Corrie A.M. Marijnen, C.J.H. van de Velde, J. F. Nagelkerke, H. J. de Bont, E. C. de Bruin, H. W. Verspaget, J.H.J.M. van Krieken
Publikováno v:
Clinical Cancer Research, 13, 5810-5
Clinical Cancer Research, 13, 19, pp. 5810-5
Clinical Cancer Research, 13, 19, pp. 5810-5
Purpose: Radiotherapy followed by total mesorectal excision surgery has been shown to significantly reduce local recurrence rates in rectal cancer patients. Radiotherapy, however, is associated with considerable morbidity. The present study evaluated
Autor:
H. J. G. M. De Bont, J. F. Nagelkerke
Publikováno v:
Chromatographia. 55:S25-S29
In the past decade numerous studies have been performed using Video Microscopy and Confocal Laser Scan Microscopy to investigate in real time the effect of compounds on cells. An overview of the techniques themselves and the necessary hardware, the m
Publikováno v:
Biochemical and Biophysical Research Communications. 240:697-700
Extracellular ATP induces bleb formation in isolated rat hepatocytes. We examined the effect of extracellular ATP on the actin cytoskeleton of these hepatocytes. Exposure to 100 microM ATP caused pronounced nuclear accumulation of G-actin. ADP, AMP,
Autor:
Marina Camatini, M. Dibisceglia, M Doldi, Patrizia Bonfanti, Anita Colombo, Chiara Urani, J. F. Nagelkerke
Publikováno v:
Scopus-Elsevier
Recently the use of in vitro systems has gained acceptance for toxicological research, since they offer several advantages. We have used primary and immortalized cell cultures to evaluate the effect of the fungicide Methyl 1-(butylcarbamoyl)benzimida
Publikováno v:
Alternatives to Laboratory Animals. 24:161-172
The effects of a widely used antitumour drug, cisplatin, on freshly isolated porcine proximal tubular cells (PPTC) in suspension were investigated. Incubation of the PPTC with 5-500μM cisplatin resulted in a decrease in mitochondrial membrane potent
Publikováno v:
Alternatives to Laboratory Animals. 22:462-473
The susceptibility to nephrotoxins of freshly isolated porcine proximal tubular cells (PPTC) and cultured PPTC in suspension were compared, with a view to using PPTC as in vitro models for studying nephrotoxicity. In a previous paper, we described ho
Publikováno v:
American Journal of Physiology-Renal Physiology. 267:F888-F899
We investigated the relationship between F-actin damage and cell detachment using nephrotoxic L-cysteine S-conjugates. In vivo S-(1,2-dichlorovinyl)-L-cysteine (DCVC) induced loss of F-actin in the S3 segment of the proximal tubule in the outer strip
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, 269(20), 14546-14552
Journal of Biological Chemistry, 269(20), 14546-14552
The relationship between mitochondrial Ca2+, oxidative stress, and a dissipation of the mitochondrial membrane potential (delta psi) was investigated in proximal tubular kidney cells. Freshly isolated proximal tubular cells from rat kidney were expos
Autor:
H. J. G. M. De Bont, J. F. Nagelkerke, A. E. Van Gompel, J. Van Steveninck, P. J. van den Broek, Michel Paardekooper
Publikováno v:
Photochemistry and Photobiology. 59:161-166
The effect of photodynamic treatment on the yeast Kluyveromyces marxianus with aluminum-phthalocyanines has been studied. It was found that the nonsulfonated sensitizer caused light-dependent loss of colony-forming capacity, whereas the mono- and tet