Výsledky vyhledávání - "J F, BRADLEY"

Two distinct phenotypes caused by two different missense mutations in the same codon of the VHL gene

Autor: J F, Bradley, D L, Collins, R N, Schimke, H N, Parrott, P G, Rothberg

Publikováno v: American journal of medical genetics. 87(2)

We have identified a family segregating von Hippel-Lindau (VHL) disease with a previously unreported T547A mutation in exon 1 of the VHL gene that causes a Tyr112 to Asn missense alteration in the protein. The mutation was identified by nucleotide se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3691c7977880fd4b4da8ff93fa79a822
https://pubmed.ncbi.nlm.nih.gov/10533030

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A deletion polymorphism due to Alu-Alu recombination in intron 2 of the retinoblastoma gene: association with human gliomas

Autor: P G, Rothberg, S, Ponnuru, D, Baker, J F, Bradley, A I, Freeman, G W, Cibis, D J, Harris, D P, Heruth

Publikováno v: Molecular carcinogenesis. 19(2)

The retinoblastoma gene (RB) encodes a tumor suppressor that is inactivated in a number of different types of cancer. We searched for gross alterations of this gene in tumors of the central nervous system by using Southern blot hybridization. A commo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e6a5ee7998e29caf4f91c1e37dfaa60a
https://pubmed.ncbi.nlm.nih.gov/9210953

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Sodium butyrate causes an increase in the block to transcriptional elongation in the c-myc gene in SW837 rectal carcinoma cells

Autor: D P, Heruth, G W, Zirnstein, J F, Bradley, P G, Rothberg

Publikováno v: The Journal of biological chemistry. 268(27)

Elevated expression of the c-myc oncogene is a frequent finding in tumors and cell lines derived from carcinomas of the colon and rectum. In a previous study we demonstrated that the differentiation agent sodium butyrate causes a rapid reduction in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ab88ee45616f140a372ac6cc0c0544c6
https://pubmed.ncbi.nlm.nih.gov/8376401

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Viability in human heart valves prepared for grafting

Autor: C. G.A. Mcgregor, J. O.d. Mcgee, J. F. Bradley, D. J. Wheatley

Publikováno v: Cardiovascular Research. 10:394-397

Viability of antibiotic sterilized and stored human heart valves obtained at routine necropsy was assessed by tissue culture and protein and collagen synthesis. Only three of 23 valves examined showed any evidence of viability, in striking contrast t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14dd9ce7b6d6aef1a46e7567493bca01
https://doi.org/10.1093/cvr/10.3.394

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Disorganisation of intermediate filament structure in alcoholic and other liver diseases

Autor: J Burns, J F Bradley, J O McGee, J A Morton, C Barbatis, J C Woods

Publikováno v: Gut. 27:765-770

The distribution of Mallory body antigens JMB1 and 2 was examined in 82 human fresh diagnostic needle liver biopsies and 28 necropsies by the indirect immunoperoxidase technique using 2 monoclonal antibodies (anti-JMB1 and 2) against Mallory bodies.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1aa63256d2e23442687d0642b2d5d52
https://doi.org/10.1136/gut.27.7.765

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Tissue culture, protein and collagen synthesis in antibiotic sterilized canine heart valves

Autor: J. O.d. Mcgee, C. G.A. Mcgregor, J. F. Bradley, D. J. Wheatley

Publikováno v: Cardiovascular research. 10(3)

Viability of canine heart valve leaflet fibroblasts was assessed after varying periods of sterilization and storage in antibiotic-nutrient solution. Tissue culture and assessment of protein and collagen synthesis showed that tissue obtained undsr opt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44057580cf02c4bb6d23a1ec1255dc6c
https://pubmed.ncbi.nlm.nih.gov/954023

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