Zobrazeno 1 - 10
of 35
pro vyhledávání: '"J Erby Wilkinson"'
Autor:
Paul E Makidon, Anna U Bielinska, Shraddha S Nigavekar, Katarzyna W Janczak, Jessica Knowlton, Alison J Scott, Nicholas Mank, Zhengyi Cao, Sivaprakash Rathinavelu, Michael R Beer, J Erby Wilkinson, Luz P Blanco, Jeffrey J Landers, James R Baker
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2954 (2008)
Hepatitis B virus infection remains an important global health concern despite the availability of safe and effective prophylactic vaccines. Limitations to these vaccines include requirement for refrigeration and three immunizations thereby restricti
Externí odkaz:
https://doaj.org/article/303f5a70839f42438c4dfc98bd0d09b2
Autor:
Felicia D. Duke Boynton, Aaron C. Ericsson, Mayu Uchihashi, Misha L. Dunbar, J. Erby Wilkinson
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-7 (2017)
Abstract Objective This study aims to demonstrate the effect of oral doxycycline on fecal microbiota of mice. Doxycycline is a common effector for control of gene expression using the tet-inducible system in transgenic mice. The effect of oral doxycy
Externí odkaz:
https://doaj.org/article/b7d77befc050458b9e57a7d2beda8320
Autor:
Sonam Bhatia, Melissa Kramer, Suzanne Russo, Payal Naik, Gayatri Arun, Kyle Brophy, Peter Andrews, Cheng Fan, Charles M. Perou, Jonathan Preall, Taehoon Ha, Dennis Plenker, David A. Tuveson, Arvind Rishi, J Erby Wilkinson, W. Richard McCombie, Karen Kostroff, David L. Spector
Publikováno v:
Cancer Res
Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer with poor patient outcomes, highlighting the unmet clinical need for targeted therapies and better model systems. Here, we developed and comprehensively characterized a diver
Autor:
Loui Rassam, Janine M. Lombard, Richard A. Miller, Sarah Nielsen, Pradeep S. Tanwar, Bo R. Rueda, J. Erby Wilkinson, Pravin Nahar, Preety Bajwa
Publikováno v:
Oncotarget
During aging, uncontrolled epithelial cell proliferation in the uterus results in endometrial hyperplasia and/or cancer development. The mTOR signaling pathway is one of the major regulators of aging as suppression of this pathway prolongs lifespan i
Autor:
Subhransu S. Sahoo, Preety Bajwa, Sarah Nielsen, Pradeep S. Tanwar, Prathima B. Nagendra, J. Erby Wilkinson, Richard A. Miller, Amanda Bielanowicz, Janine M. Lombard
Publikováno v:
Oncotarget
Ovarian cancer is a disease of older women. However, the molecular mechanisms of ovarian aging and their contribution to the pathogenesis of ovarian cancer are currently unclear. mTOR signalling is a major regulator of aging as suppression of this pa
Autor:
Direna Alonso-Curbelo, Emma M Schatoff, Maria Paz Zafra Martin, J. Erby Wilkinson, Lukas E. Dow
Publikováno v:
Molecular Cancer Research. 18:A49-A49
Defining the effect of specific oncogenic mutations on tumor behavior and therapy response is essential for developing effective treatment strategies and realizing the promise of precision medicine. KRAS is the most frequently mutated oncogene in hum
Autor:
Aaron C. Ericsson, Felicia D. Duke Boynton, Mayu Uchihashi, J. Erby Wilkinson, Misha L Dunbar
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-7 (2017)
BMC Research Notes
BMC Research Notes
Objective This study aims to demonstrate the effect of oral doxycycline on fecal microbiota of mice. Doxycycline is a common effector for control of gene expression using the tet-inducible system in transgenic mice. The effect of oral doxycycline on
Autor:
Ying Jin, Molly Hammell, Yilin Tai, Linda Van Aelst, Jae Seok Roe, Jia Ray Yu, Christopher R. Vakoc, J. Erby Wilkinson
Publikováno v:
Genes & Development. 29:250-261
The mechanisms by which TGF-β promotes lung adenocarcinoma (ADC) metastasis are largely unknown. Here, we report that in lung ADC cells, TGF-β potently induces expression of DOCK4, but not other DOCK family members, via the Smad pathway and that DO
Autor:
Susan Ciotti, Stephen Gracon, Rone Eisma, Vladislav A. Dolgachev, J. Erby Wilkinson, James R. Baker, Mark R. Hemmila
Publikováno v:
Journal of burn careresearch : official publication of the American Burn Association. 37(2)
The aim of this study is to investigate the antimicrobial efficacy of two different nanoemulsion (NE) formulations against Gram-positive and Gram-negative bacteria in an in vivo rodent scald burn model. Male Sprague-Dawley rats were anesthetized and
Autor:
Scott D. Pletcher, David E. Harrison, Randy Strong, James W. Simpkins, J. Erby Wilkinson, Clinton M. Astle, Martin A. Javors, David B. Allison, Elizabeth Fernandez, Hani Atamna, Bruce N. Ames, Kevin Flurkey, James F. Nelson, Richard A. Miller, Nancy L. Nadon, Daniel L. Smith
Publikováno v:
Aging Cell
Four agents — acarbose (ACA), 17-α-estradiol (EST), nordihydroguaiaretic acid (NDGA), and methylene blue (MB) — were evaluated for lifespan effects in genetically heterogeneous mice tested at three sites. Acarbose increased male median lifespan