Zobrazeno 1 - 10
of 238
pro vyhledávání: '"J Edwin Blalock"'
Autor:
Teodora Nicola, Nancy Wenger, Xin Xu, Michael Evans, Luhua Qiao, Gabriel Rezonzew, Youfeng Yang, Tamas Jilling, Camilla Margaroli, Kristopher Genschmer, Kent Willis, Namasivayam Ambalavanan, J. Edwin Blalock, Amit Gaggar, Charitharth Vivek Lal
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Bronchopulmonary dysplasia (BPD) is a chronic lung disease of prematurity. Exposure to noxious stimuli such as hyperoxia, volutrauma, and infection in infancy can have long-reaching impacts on lung health and predispose towards the developme
Externí odkaz:
https://doaj.org/article/194ba58ce72542aaab48a844418a8020
Autor:
Xue-Ke Zhao, Pulin Che, Ming-Liang Cheng, Quan Zhang, Mao Mu, Hong Li, Yuan Luo, Yue-Dong Liang, Xin-Hua Luo, Chang-Qing Gao, Patricia L Jackson, J Michael Wells, Yong Zhou, Meng Hu, Guoqiang Cai, Victor J Thannickal, Chad Steele, J Edwin Blalock, Xiaosi Han, Ching-Yi Chen, Qiang Ding
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167451 (2016)
Tumor necrosis factor-alpha (TNF-α) is a potent pro-inflammatory mediator and its expression is up-regulated in chronic obstructive pulmonary disease (COPD). Tristetraprolin (TTP) is implicated in regulation of TNF-α expression; however, whether TT
Externí odkaz:
https://doaj.org/article/f6e719c7215c425cbbbf0b028f485380
Autor:
Derek W Russell, J Edwin Blalock
Publikováno v:
eLife, Vol 4 (2015)
Nanoparticles of carbon black in cigarette smoke trigger inflammation in the lung.
Externí odkaz:
https://doaj.org/article/4cb6154d47944eeba6f52b55ffff3f6e
Autor:
Saskia A Overbeek, Saskia Braber, Pim J Koelink, Paul A J Henricks, Esmaeil Mortaz, Adele T LoTam Loi, Patricia L Jackson, Johan Garssen, Gerry T M Wagenaar, Wim Timens, Leo Koenderman, J Edwin Blalock, Aletta D Kraneveld, Gert Folkerts
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55612 (2013)
Cigarette smoking induces inflammatory responses in all smokers and is the major risk factor for lung disease such as chronic obstructive pulmonary disease (COPD). In this progressive disease, chronic inflammation in the lung contributes to lung tiss
Externí odkaz:
https://doaj.org/article/a5287e64a4674b68bf191649ff2fd891
Autor:
Camilla Margaroli, Matthew C. Madison, Liliana Viera, Derek W. Russell, Amit Gaggar, Kristopher R. Genschmer, J. Edwin Blalock
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
Chronic obstructive pulmonary disease (COPD) is a debilitating chronic disease and the third-leading cause of mortality worldwide. It is characterized by airway neutrophilia, promoting tissue injury through release of toxic mediators and proteases. R
Externí odkaz:
https://doaj.org/article/aaf563e978dd471ab4a21e262926c072
Autor:
Kristopher R. Genschmer, Matthew Madison, Liliana Viera, Camilla Margaroli, Amit Gaggar, J. Edwin Blalock, Derek W. Russell
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L694-L699
Protamine sulfate facilitates the removal of neutrophil elastase (NE) from the surface of extracellular vesicles from activated neutrophils. This “free” NE is no longer protected from inhibition by its endogenous anti-protease, α-1-anti-trypsin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16ad07b80dd192931025e9296e75599b
https://doi.org/10.1152/ajplung.00057.2023
https://doi.org/10.1152/ajplung.00057.2023
Autor:
Sarah W. Robison, JinDong Li, Liliana Viera, Jonathan P. Blackburn, Rakesh P. Patel, J. Edwin Blalock, Amit Gaggar, Xin Xu
Publikováno v:
JCI Insight, Vol 6, Iss 7 (2021)
Proline-glycine-proline (PGP) and its acetylated form (Ac-PGP) are neutrophil chemoattractants generated by collagen degradation, and they have been shown to play a role in chronic inflammatory disease. However, the mechanism for matrikine regulation
Externí odkaz:
https://doaj.org/article/518e8c111445444bb3b328b245fc6a54
Autor:
Gregory A. Payne, Nirmal S. Sharma, Charitharth V. Lal, Chunyan Song, Lingling Guo, Camilla Margaroli, Liliana Viera, Siva Kumar, Jindong Li, Dongqi Xing, Melanie Bosley, Xin Xu, J. Michael Wells, James F. George, Jose Tallaj, Massoud Leesar, J. Edwin Blalock, Amit Gaggar
Publikováno v:
JCI Insight, Vol 6, Iss 6 (2021)
Altered inflammation and tissue remodeling are cardinal features of cardiovascular disease and cardiac transplant rejection. Neutrophils have increasingly been understood to play a critical role in acute rejection and early allograft failure; however
Externí odkaz:
https://doaj.org/article/d53850bcfbaa4d7e9a45089663f41232
Autor:
Gregory A. Payne, Jindong Li, Xin Xu, Patricia Jackson, Hongwei Qin, David M. Pollock, J. Michael Wells, Suzanne Oparil, Massoud Leesar, Rakesh P. Patel, J. Edwin Blalock, Amit Gaggar
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract The extracellular matrix (ECM) is a dynamic, bioactive structure critical to organ development, structure and function. Excessive remodeling of the ECM is a hallmark of a variety of inflammatory conditions including vascular disease. Endothe
Externí odkaz:
https://doaj.org/article/a02a41bb53f14b3b8aaea863666146da
Autor:
Teodora Nicola, Nancy Wenger, Xin Xu, Michael Evans, Gabriel Rezonzew, Luhua Qiao, Youfeng Yang, Namasivayam Ambalavanan, J Edwin Blalock, Amit Gaggar, Charitharth Vivek Lal
Bronchopulmonary dysplasia (BPD) is a chronic lung disease of prematurity. Exposure to noxious stimuli such as hyperoxia, volutrauma, and infection in infancy can have long-reaching impacts on lung health and predispose towards the development of con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcd939f235f4a2acf1eb335220308437
https://doi.org/10.1101/2023.03.02.529882
https://doi.org/10.1101/2023.03.02.529882
