Zobrazeno 1 - 10
of 95
pro vyhledávání: '"J Edmiston"'
Autor:
Limin Wu, Joon Yong Chung, Tian Cao, Gina Jin, William J. Edmiston, Suzanne Hickman, Emily S. Levy, Jordyn A. Whalen, Eliza Sophie LaRovere Abrams, Alexei Degterev, Eng H. Lo, Lorenzo Tozzi, David L. Kaplan, Joseph El Khoury, Michael J. Whalen
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-16 (2021)
Abstract Traumatic brain injury (TBI) is a leading cause of death and disability with no specific effective therapy, in part because disease driving mechanisms remain to be elucidated. Receptor interacting protein kinases (RIPKs) are serine/threonine
Externí odkaz:
https://doaj.org/article/c772f18f6a714ef4a0700b6cdba662be
Akademický článek
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Autor:
M I McCormick, E P Fakan, G Vamvounis, S Bosshard, C Moad, E Smyth, P Gatenby, J Edmiston, K Patel, B J M Allan
Publikováno v:
ICES Journal of Marine Science.
This study experimentally explored the influence of periodic consumption of polystyrene (PS) microplastic fragments on the body condition and fitness of a tropical marine fish. Adult damselfish, Acanthochromis polyacanthus, were pulse fed microplasti
Autor:
Suk-Tak Chan, Limin Wu, Jonathan O. Lipton, Fortunate F. Chifamba, Yin-Ching I Chen, Gina Jin, William J Edmiston, Kenneth K. Kwong, William P. Meehan, Emily Levy, Rebekah Mannix, Michael J. Whalen
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 41:3260-3272
Cerebrovascular reactivity (CVR) deficits in adolescents with concussion may persist after resolution of neurological symptoms. Whether or not CVR deficits predict long term neurological function is unknown. We used adolescent mice closed head injury
Autor:
Joon Yong Chung, Tanya Songtachalert, Alexei Degterev, David L. Kaplan, Gina Jin, Aliyah Sarro-Schwartz, Neil D. Fernandes, Michael J. Whalen, William J Edmiston, Saef Izzy, Siddharth Balachandran, So Hee Ahn, Sevda Lule, Eng H. Lo, Limin Wu
Publikováno v:
J Cereb Blood Flow Metab
Receptor-interacting protein kinase-1 (RIPK1) is a master regulator of cell death and inflammation, and mediates programmed necrosis (necroptosis) via mixed-lineage kinase like (MLKL) protein. Prior studies in experimental intracerebral hemorrhage (I
Autor:
Jordyn A. Whalen, William J Edmiston, Tian Cao, Michael J. Whalen, Limin Wu, Lorenzo Tozzi, Suzanne E. Hickman, Alexei Degterev, Gina Jin, Eng H. Lo, Emily Levy, Joseph El Khoury, David L. Kaplan, Eliza Sophie LaRovere Abrams, Joon Yong Chung
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-16 (2021)
Cell Death & Disease
Cell Death & Disease
Traumatic brain injury (TBI) is a leading cause of death and disability with no specific effective therapy, in part because disease driving mechanisms remain to be elucidated. Receptor interacting protein kinases (RIPKs) are serine/threonine kinases
Autor:
Mark C. Poznansky, Joon Yong Chung, William J Edmiston, Michael J. Whalen, Ruxandra F. Sîrbulescu, Sonya A. Poznansky
Publikováno v:
Journal of Neurotrauma. 36:2579-2589
Cerebral contusion causes neurological dysfunction mediated in part by inflammatory responses to injury. B lymphocytes are dynamic regulators of the immune system that have not been systematically studied in traumatic brain injury (TBI). We showed pr
Autor:
Limin, Wu, Suk-Tak, Chan, William J, Edmiston, Gina, Jin, Emily S, Levy, Kenneth K, Kwong, Rebekah, Mannix, William P, Meehan, Fortunate F, Chifamba, Jonathan O, Lipton, Michael J, Whalen, Yin-Ching I, Chen
Publikováno v:
J Cereb Blood Flow Metab
Cerebrovascular reactivity (CVR) deficits in adolescents with concussion may persist after resolution of neurological symptoms. Whether or not CVR deficits predict long term neurological function is unknown. We used adolescent mice closed head injury
Autor:
Fumiaki Oka, Mohammad A. Yaseen, Sanem Aslıhan Aykan, Gina Jin, Andrea M. Harriott, Tao Qin, Michael J. Whalen, Hang Lee, David Y. Chung, Sava Sakadžić, Sreekanth Kura, Cenk Ayata, William J Edmiston, David A. Boas
Publikováno v:
J Cereb Blood Flow Metab
Aneurysmal subarachnoid hemorrhage (SAH) leads to significant long-term cognitive deficits, which can be associated with alterations in resting state functional connectivity (RSFC). However, modalities such as fMRI—which is commonly used to assess
Autor:
Eng H. Lo, John S. Sherwood, Limin Wu, Joseph El Khoury, Samantha Martin, Josephine Lok, Tanya Songtachalert, Saef Izzy, Emily Levy, Lauren M. McAllister, William J Edmiston, Sevda Lule, Joon Yong Chung, Michael J. Whalen, Erin M. Buckley, Nicolas Krapp, Suzanne E. Hickman, Bharat Sanders, David L. Kaplan, Shuzhen Guo
Publikováno v:
Journal of Neurotrauma. 36:370-379
Important differences in the biology of focal and diffuse traumatic brain injury (TBI) subtypes may result in unique pathophysiological responses to shared molecular mechanisms. Interleukin-1 (IL-1) signaling has been tested as a potential therapeuti