Zobrazeno 1 - 10
of 45
pro vyhledávání: '"J E. Semple"'
Autor:
Farbod Shojaei, J E. Semple, Che Fang, Jill M. Ricono, Fairooz Kabbinavar, Bob Goodenow, Mireille Gillings
Publikováno v:
Cancer Research. 82:LB526-LB526
92130MLL1 (mixed lineage leukemia1) interaction with WDR5 (WD repeat domain 5) is critical for MLL1 histone methyl transferase (H3K4me) activity leading to transcriptional regulation of gene expression. MLL1 dysregulation such as its translocation at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11212f374e997646a3ff451b34808b74
https://doi.org/10.1158/1538-7445.am2022-lb526
https://doi.org/10.1158/1538-7445.am2022-lb526
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 9:2573-2578
Rigid benzolactam P3-P2 dipeptide mimics were designed and prepared as potential inhibitors of blood coagulation factor Xa. Methoxy substitution of the tetrahydrobenzazepinone scaffold led to potent and selective inhibitors. The synthesis and biologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91e1934325ea4b3218d31a6b618f98a
https://doi.org/10.1016/s0960-894x(99)00417-5
https://doi.org/10.1016/s0960-894x(99)00417-5
Autor:
W. E. Rote, B. M. Richard, E. Zhang, Lim Ml, Nutt Rf, Dempsey E, J. E. Semple, Alexander Tulinsky, Odile E. Levy, Ripka Wc, Reiner J
Publikováno v:
Journal of Medicinal Chemistry. 39:4527-4530
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51505ba1c36d5dea7bbe2600b488dbba
https://doi.org/10.1021/jm960607j
https://doi.org/10.1021/jm960607j
Autor:
M. I. Weinhouse, Brian M. Shamblin, J. E. Semple, Yu Ge, Susan Yoshiko Tamura, P. Leon, R. J. Ardecky, Ruth F. Nutt, S. H. Carpenter, William C. Ripka
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb50f8d7de7cf4f82a1771fe55e04e33
https://doi.org/10.1002/chin.199637274
https://doi.org/10.1002/chin.199637274
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c534c2262995c0b6f18bb611465be70
https://doi.org/10.1002/chin.199710122
https://doi.org/10.1002/chin.199710122
Autor:
J. E. Semple, W. M. Murray
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02facc5d9158ed19577fe94cc02256a4
https://doi.org/10.1002/chin.199711036
https://doi.org/10.1002/chin.199711036
Autor:
D. C. Rowley, Yu Ge, B. M. Richard, R. J. Ardecky, Erick A. Goldman, Daniel V. Siev, Timothy D. Owens, K. Haakanson, Alexander Tulinsky, Susan Yoshiko Tamura, Nathaniel K. Minami, William C. Ripka, S. H. Carpenter, Terence K. Brunck, T. G. Nolan, Ruth F. Nutt, Theresa Ha-Uong, J. E. Semple
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47682941c0c0982370f559c97d6112f2
https://doi.org/10.1002/chin.199708204
https://doi.org/10.1002/chin.199708204
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7147b8f0bfbe6a0d4ba6084cd261ae44
https://doi.org/10.1002/chin.199725191
https://doi.org/10.1002/chin.199725191
Autor:
Susan Yoshiko Tamura, Terence K. Brunck, Nathaniel K. Minami, William C. Ripka, Ruth F. Nutt, J. E. Semple
Publikováno v:
ChemInform. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07c702464b0498da0f5596000b0547cb
https://doi.org/10.1002/chin.199804182
https://doi.org/10.1002/chin.199804182