Výsledky vyhledávání

A randomized clinical trial of valacyclovir in multiple sclerosis

Autor: J E Whitman, Otto Rapalino, M Shieh, J B Zabriskie, Dharam V. Ablashi, Randall C. Edgell, C. Plank, B Shahan, J E Friedman, Robert D. Zimmerman, D Sheng

Publikováno v: Multiple Sclerosis Journal. 11:286-295

Objective: The human Herpesvirus type-6 (HHV-6) has been implicated in multiple sclerosis (MS). Valacyclovir is an antiviral agent with an excellent safety profile. A two-year, placebo-controlled, double-blind study was conducted to (1) ascertain if

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381d013ba87119b32c9aa128eca82a02
https://doi.org/10.1191/1352458505ms1185oa

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The association of the human herpesvirus-6 and MS

Autor: J E Whitman, G Cu, Marjaleena Koskiniemi, J E Friedman, Mark A. Edgar, Antti Vaheri, John B. Zabriskie, Michael J. Lyons, D V Ablashl

Publikováno v: Multiple Sclerosis. 5:355-362

Given the clinical and pathological nature of multiple sclerosis (MS), a viral infection has long been hypothesized as part of the etiology. In this study we investigated the possibility that the human herpesvirus-6 (HHV-6) is present in a dormant or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0c3988f8837d89d740ad64de1f3858
https://doi.org/10.1191/135245899678846311

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Lack of serologic association of human herpesvirus-8 (KSHV) in patients with monoclonal gammopathy of undetermined significance with and without progression to multiple myeloma

Autor: D V, Ablashi, L, Chatlynne, D, Thomas, D, Bourboulia, M B, Rettig, R A, Vescio, D, Viza, P, Gill, R A, Kyle, J R, Berenson, J E, Whitman

Publikováno v: Blood. 96(6)

Because human herpesvirus-8 (HHV-8) DNA has been found in multiple myeloma (MM) patients by polymerase chain reaction, it was suggested that HHV-8 may play a role in the transformation of monoclonal gammopathy of undetermined significance (MGUS) to M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5786db17e9a0326ecbfef49e8c17d2e5
https://pubmed.ncbi.nlm.nih.gov/10979981

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Detection and titration of human herpesvirus-8-specific antibodies in sera from blood donors, acquired immunodeficiency syndrome patients, and Kaposi's sarcoma patients using a whole virus enzyme-linked immunosorbent assay

Autor: L G, Chatlynne, W, Lapps, M, Handy, Y Q, Huang, R, Masood, A S, Hamilton, J W, Said, H P, Koeffler, M H, Kaplan, A, Friedman-Kien, P S, Gill, J E, Whitman, D V, Ablashi

Publikováno v: Blood. 92(1)

A human herpesvirus-8 (HHV-8) enzyme-linked immunosorbent assay (ELISA) with a whole virus lysate as antigen was developed and used to measure the seroprevalence rate and levels of IgG antibodies to HHV-8 in sera/plasma of various patient groups and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bc050e1e85a3b43e87a7b3f1d9bd9141
https://pubmed.ncbi.nlm.nih.gov/9639499

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Longitudinal follow-up of two AIDS patients for active human herpesvirus-6 (HHV-6) infection

Autor: D V, Ablashi, L G, Chatlynne, J E, Whitman

Publikováno v: In vivo (Athens, Greece). 11(5)

Because of the demonstrated presence of Human Herpesvirus-6 (HHV-6) in various tissues and organs of HIV-1 infected AIDS patients, and its implication in the pathogenesis of AIDS, we followed two AIDS patients for active HHV-6 infection for two years

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::72df24ce4c371e100071a9b494e7c6a8
https://pubmed.ncbi.nlm.nih.gov/9427039

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Comparison of Neutralization and Hemagglutination-Inhibition Techniques for Measuring Mumps Antibody

Autor: Robert R. Roehm, Maurice R. Hilleman, Lampson Gp, J. E. Whitman, Eugene B. Buynak, David H. Morton

Publikováno v: Experimental Biology and Medicine. 125:1068-1071

SummaryMumps hemagglutinating antigen treated with Tween 80 and ether showed 2- to 4-fold enhancement of hemagglutinin titer. The hemagglutinating activity of the treated antigen was stable on free...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47bc4f339a801afaa4518a6e9d26d3e1
https://doi.org/10.3181/00379727-125-32278

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Establishing Industrial/Academic Partnerships in Biotechnology

Autor: Jr J. E. Whitman

Publikováno v: Interdisciplinary Science Reviews. 14:130-132

(1989). Establishing Industrial/Academic Partnerships in Biotechnology. Interdisciplinary Science Reviews: Vol. 14, No. 2, pp. 130-132.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::37a83295bf1362ef19e47e836573238f
https://doi.org/10.1179/isr.1989.14.2.130

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An unusual case of feline leukemia and an associated syncytium-forming virus

Autor: J E, Whitman, K O, Cockrell, W T, Hall, C E, Gilmore

Publikováno v: American journal of veterinary research. 36(7)

A 3-year-old female Siamese cat was admitted to a local animal hospital with a history of recent extreme lethargy and anorexia. A hemorrhagic tumor was removed from an area of oral buccal skin and diagnosed histopathologically as lymphosarcoma. Rapid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3d0fe07b87a4825d83de144ab8aec04
https://pubmed.ncbi.nlm.nih.gov/167623

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