Výsledky vyhledávání - "J E Obradovich"

Granular Cell Tumor of the Canine Central Nervous System: Two Cases

Autor: J. E. Obradovich, Richard A Lecouteur, Andrew W. Bollen, Robert Higgins, Beverly K. Sturges, Karen M. Vernau

Publikováno v: Veterinary Pathology. 38:620-627

Although pure granular cell tumors have been reported in various sites in the dog, only one tumor has been reported in the central nervous system. Two dogs presented with neurologic signs had brain lesions detected by magnetic resonance imaging in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6fbe9cd851036afeb45e85e19945e2e
https://doi.org/10.1354/vp.38-6-620

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A retrospective analysis of the efficacy of Oncept vaccine for the adjunct treatment of canine oral malignant melanoma

Autor: J M, Ottnod, R C, Smedley, R, Walshaw, J G, Hauptman, M, Kiupel, J E, Obradovich

Publikováno v: Veterinary and comparative oncology. 11(3)

Oral malignant melanoma (OMM) in the dog is often locally aggressive with a high metastatic potential and there are few treatment options that have been demonstrated to improve outcome of this disease. The purpose of this study was to determine wheth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9fc7405aae1f098268c25294c786d209
https://pubmed.ncbi.nlm.nih.gov/23909996

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Carotid Body Tumors in the Dog Eleven Cases (1978-1988)

Autor: J E Obradovich, Barbara E. Powers, Richard Walshaw, Stephen J. Withrow

Publikováno v: Journal of Veterinary Internal Medicine. 6:96-101

Case records of 11 dogs with histologically confirmed carotid body tumors were reviewed. Surgical excision had been attempted in ten dogs with carotid body tumors, and one dog had been euthanatized at diagnosis. There were no intraoperative deaths bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3f2c6f32c149876ae1a14ed858c611
https://doi.org/10.1111/j.1939-1676.1992.tb03158.x

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Efficacy of pyridoxine to ameliorate the cutaneous toxicity associated with doxorubicin containing pegylated (Stealth) liposomes: a randomized, double-blind clinical trial using a canine model

Autor: D M, Vail, R, Chun, D H, Thamm, L D, Garrett, A J, Cooley, J E, Obradovich

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 4(6)

A cutaneous reaction termed palmar-plantar erythrodysesthesia (PPES) or hand-foot syndrome can be dose limiting for Doxil, a doxorubicin containing pegylated (Stealth) liposome. The objective of this study was to determine the ability of concomitant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c0c00b085d251a2f7b51433407978f77
https://pubmed.ncbi.nlm.nih.gov/9626479

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Assessment of potential doubling time (Tpot), argyrophilic nucleolar organizer regions (AgNOR), and proliferating cell nuclear antigen (PCNA) as predictors of therapy response in canine non-Hodgkin's lymphoma

Autor: D M, Vail, W C, Kisseberth, J E, Obradovich, F M, Moore, C A, London, E G, MacEwen, M A, Ritter

Publikováno v: Experimental hematology. 24(7)

The predictive potential of several proliferation indices for therapeutic outcome was investigated in 55 dogs with spontaneously occurring non-Hodgkin's lymphoma (NHL). Indices included potential doubling time (Tpot), argyrophilic nucleolar organizer

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https://pubmed.ncbi.nlm.nih.gov/9197321

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Liposome-encapsulated muramyl tripeptide phosphatidylethanolamine adjuvant immunotherapy for splenic hemangiosarcoma in the dog: a randomized multi-institutional clinical trial

Autor: D M, Vail, E G, MacEwen, I D, Kurzman, R R, Dubielzig, S C, Helfand, W C, Kisseberth, C A, London, J E, Obradovich, B R, Madewell, C O, Rodriguez

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 1(10)

Canine splenic hemangiosarcoma (HSA) is a spontaneous tumor with high metastatic potential. Despite surgical excision, most dogs die within 2 months of diagnosis as a result of widespread visceral metastasis. This study was designed to determine the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::81e43d31821820210c2857abe5e0bc00
https://pubmed.ncbi.nlm.nih.gov/9815908

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Current studies of liposome muramyl tripeptide (CGP 19835A lipid) therapy for metastasis in spontaneous tumors: a progress review

Autor: W C Kisseberth, Janean Fidel, Evan T. Keller, B. Kitchell, J E Obradovich, R C Rosenthal, Ilene D. Kurzman, Stuart C. Helfand, David M. Vail, E G MacEwen, Carlos O. Rodriguez, C L London, Leslie E. Fox, Bruce R. Madewell, S. Susaneck, M. Rosenberg

Publikováno v: Journal of drug targeting. 2(5)

Targeted delivery of macrophage activating agents is an attractive approach to treat micrometastatic disease. Liposome-encapsulated muramyl tripeptide phosphatidylethanolamine (L-MTP-PE) is a potent activator of monocytes/macrophages in humans, mice,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d626cc1671609b2ebe7de8496210c1
https://pubmed.ncbi.nlm.nih.gov/7704483

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Toxicoses and efficacy associated with administration of mitoxantrone to cats with malignant tumors

Autor: G K, Ogilvie, A S, Moore, J E, Obradovich, R E, Elmslie, D M, Vail, R C, Straw, M D, Salmon, M K, Klein, S W, Atwater, P E, Ciekot

Publikováno v: Journal of the American Veterinary Medical Association. 202(11)

Eighty-seven cats with histologically confirmed malignant tumors were used in a prospective study to determine the toxicity of mitoxantrone, a dihydroxyquinone derivative of anthracene, which was administered at 21-day intervals at dosages ranging fr

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https://pubmed.ncbi.nlm.nih.gov/8320152

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Toxicoses associated with administration of mitoxantrone to dogs with malignant tumors

Autor: G K, Ogilvie, J E, Obradovich, R E, Elmslie, D M, Vail, A S, Moore, C R, Curtis, R C, Straw, K, Dickinson, M F, Cooper, S J, Withrow

Publikováno v: Journal of the American Veterinary Medical Association. 198(9)

One hundred twenty-nine dogs with histologically confirmed malignant tumors were used in a prospective study to determine the toxicity of the new dihydroxyquinone derivative of anthracene, mitoxantrone, which was administered IV at 21-day intervals a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::502e8734334eed0144c25bfaac3ff72e
https://pubmed.ncbi.nlm.nih.gov/2061176

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