Zobrazeno 1 - 10
of 26
pro vyhledávání: '"J E Oakes"'
Publikováno v:
International Journal of Inflammation, Vol 2012 (2012)
In this study we show that murine and human neutrophils are capable of secreting IP-10 in response to communication from the HSV-1 infected cornea and that they do so in a time frame associated with the recruitment of CD8+ T cells and CXCR3-expressin
Externí odkaz:
https://doaj.org/article/b416b809c5af4aa98994f1a2ee275876
Publikováno v:
The Journal of Immunology. 153:2258-2265
Herpes simplex virus type 1 (HSV-1) infection of the murine cornea induces an intense inflammatory response that can lead to permanent blindness. We tested whether IL-10, a cytokine that has anti-inflammatory properties, could suppress the developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::769404de2e42fbd1bd42e6bd5bac3e2e
https://doi.org/10.4049/jimmunol.153.5.2258
https://doi.org/10.4049/jimmunol.153.5.2258
Publikováno v:
The Journal of Immunology. 153:232-240
Neutrophils and Langerhans cells participate in inflammatory reactions within the human cornea. Because granulocyte-macrophage (GM)-CSF is a chemotactic and activating factor for these two cell types, we investigated whether this cytokine is produced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75ff2a895932ad24664199b78afa7ad1
https://doi.org/10.4049/jimmunol.153.1.232
https://doi.org/10.4049/jimmunol.153.1.232
Publikováno v:
Investigative ophthalmologyvisual science. 42(3)
The purpose of this study was to determine whether human corneal epithelial cells and keratocytes synthesize both the soluble and membrane forms of the type II IL-1 receptor (IL-1RII).Primary cell cultures of human corneal epithelial cells and kerato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d6e3ec3f8c5f3d60b297186d43b424b
https://pubmed.ncbi.nlm.nih.gov/11222530
https://pubmed.ncbi.nlm.nih.gov/11222530
Publikováno v:
Journal of leukocyte biology. 69(1)
We investigated whether IL-10 produced endogenously would influence the development of HSV-1-induced acute corneal disease. Murine corneal epithelial cells and fibroblasts cultured in vitro expressed IL-10 mRNA and protein constitutively and also IL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4af2f416f7335a83236a5ae7b4e3c5b
https://pubmed.ncbi.nlm.nih.gov/11200059
https://pubmed.ncbi.nlm.nih.gov/11200059
Publikováno v:
Investigative ophthalmologyvisual science. 41(12)
To determine whether substance P (SP), a neuropeptide with proinflammatory properties, specifically interacts with human corneal epithelial cells to stimulate synthesis of the chemokines interleukin (IL)-8, monocyte chemo-attractant protein (MCP)-1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8c1d735eb1e723c70878823a1f0e6e3
https://pubmed.ncbi.nlm.nih.gov/11053288
https://pubmed.ncbi.nlm.nih.gov/11053288
Publikováno v:
Investigative ophthalmologyvisual science. 41(6)
To investigate the role macrophages play in controlling herpes simplex virus (HSV)-1 replication after infection of the murine cornea.Macrophage depletion in selected tissues before or after virus infection was achieved by repeated subconjunctival (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35d5f1b29e4c00dd183c5252e7077d23
https://pubmed.ncbi.nlm.nih.gov/10798656
https://pubmed.ncbi.nlm.nih.gov/10798656
Publikováno v:
Investigative ophthalmologyvisual science. 39(10)
Neutrophils are the most prominent cell type to migrate initially into the herpes simplex virus type 1 (HSV-1)-infected murine cornea. The role the C-X-C chemokines macrophage inflammatory protein (MIP)-2 and KC play in promoting this response was in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ff1e5bc22cbefe032b67258007537802
https://pubmed.ncbi.nlm.nih.gov/9727408
https://pubmed.ncbi.nlm.nih.gov/9727408
Publikováno v:
Investigative ophthalmologyvisual science. 37(6)
To determine whether human corneal epithelial cells and keratocytes produce chemokines regulated upon activation, normal T-cell expressed and secreted (RANTES) protein and monocyte chemotactic protein-1 (MCP-1) after exposure to proinflammatory cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcb83f60621521a27cff15675abe4cca
https://pubmed.ncbi.nlm.nih.gov/8631642
https://pubmed.ncbi.nlm.nih.gov/8631642
Publikováno v:
Investigative ophthalmologyvisual science. 36(2)
To determine whether interleukin-6 (IL-6) can be synthesized by human corneal keratocytes and epithelial cells.Epithelial cells and keratocytes isolated from the same donor corneas were grown in vitro. After 2 to 3 passages, the cultures were exposed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3158a3e8d8074dba87bb117b67f4885
https://pubmed.ncbi.nlm.nih.gov/7843904
https://pubmed.ncbi.nlm.nih.gov/7843904