Zobrazeno 1 - 10
of 14
pro vyhledávání: '"J E Holder"'
Publikováno v:
British Journal of Dermatology. 138:418-421
The value of pigmented lesion clinics (PLCs) for the early detection and treatment of malignant melanoma has been questioned. We have examined the effect of the introduction of a PLC on the referral interval between patients with melanoma presenting
Autor:
R.A.C. Graham-Brown, K. Whaley, J.F. Bourke, A. Fletcher, J. North, P.S. Colloby, J. E. Holder
Publikováno v:
Clinical and Experimental Dermatology. 22:287-290
A 47-year-old man presented with diarrhoea, acquired hypogammaglobulinaemia and a cutaneous graft-versus-host-like reaction in association with a spindle cell thymoma. Graft-versus-host reactions usually occur following allogeneic transplantation or
Autor:
George Paxinos, D G Woodhouse, A J Churchyard, R. M. Kalnins, Gavin Fabinyi, Frederick A. O. Mendelsohn, Geoffrey A. Donnan, S.J. Kaczmarczyk, J E Holder, P J Chilco
Publikováno v:
Molecular Neurobiology. 5:421-433
A series of compensatory mechanisms within the dopaminergic system have been shown to maintain clinical function in the presence of dopamine loss. Experimental evidence for increased presynaptic dopamine turnover owing to increased dopamine synthesis
Publikováno v:
Clinical and Experimental Dermatology. 24:57-59
A randomized study was undertaken to investigate the effectiveness of a chart as an aid to memory illustrating the topical medication most frequently prescribed both in the dermatology clinic, and in general practice. One hundred subjects, half new r
Publikováno v:
British Journal of Dermatology. 134:777-779
Cyclosporin is a highly effective treatment for severe psoriasis and atopic dermatitis. However, both inter- and intrapatient gastrointestinal absorption of the conventional formulation of cyclosporin (Sandimmun) are very variable, ranging from 20 to
Publikováno v:
British Journal of Dermatology. 134:519-521
A 67-year-old woman presented with a scaly, erythematous plaque, for which a clinical diagnosis of Bowen's disease was made. However, incisional biopsy established the diagnosis of amelanotic superficial spreading malignant melanoma. Biopsy thus avoi
Publikováno v:
European journal of immunology. 31(3)
A diverse repertoire among peripheral T cells is established in early life by thymic export when the naive T cell pool is first formed. In contrast, during adult life the thymus has been thought to play only a minor role in T cell homeostasis. As ind
Publikováno v:
Immunology. 98(3)
We have studied the appearance and phenotype of recent thymic emigrants in blood, spleen and lymph nodes (LN) of neonatal lambs. Using in situ labelling of thymocytes with fluoroscein isothiocyanate (FITC), we examined the expression of the LN homing
Publikováno v:
Clinical and experimental dermatology. 24(2)
A randomized study was undertaken to investigate the effectiveness of a chart as an aid to memory illustrating the topical medication most frequently prescribed both in the dermatology clinic, and in general practice. One hundred subjects, half new r
Publikováno v:
The British journal of dermatology. 137(3)
The pathogenesis of psoriasis appears to depend on T cells, which have been proposed to mediate the disease through an autoimmune process. To test this hypothesis we have propagated four T-cell lines from biopsies of psoriatic skin lesions by antigen