Výsledky vyhledávání - "J E Friedman"

A randomized clinical trial of valacyclovir in multiple sclerosis

Autor: J E Whitman, Otto Rapalino, M Shieh, J B Zabriskie, Dharam V. Ablashi, Randall C. Edgell, C. Plank, B Shahan, J E Friedman, Robert D. Zimmerman, D Sheng

Publikováno v: Multiple Sclerosis Journal. 11:286-295

Objective: The human Herpesvirus type-6 (HHV-6) has been implicated in multiple sclerosis (MS). Valacyclovir is an antiviral agent with an excellent safety profile. A two-year, placebo-controlled, double-blind study was conducted to (1) ascertain if

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381d013ba87119b32c9aa128eca82a02
https://doi.org/10.1191/1352458505ms1185oa

Zobrazit plný text záznamu

Effects of overexpression of human GLUT4 gene on maternal diabetes and fetal growth in spontaneous gestational diabetic C57BLKS/J Lepr(db/+) mice

Autor: T Ishizuka, P Klepcyk, S Liu, L Panko, E M Gibbs, J E Friedman

Publikováno v: Diabetes. 48:1061-1069

During gestation, heterozygous C57BLKS/J-Lepr(db/+) mice develop spontaneous gestational diabetes mellitus (GDM), and the newborn fetuses are macrosomic compared with offspring from wild-type (+/+) mothers. To investigate the effects of the leptin re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf10a2abb3ff09b2e9d7c6819c80138
https://doi.org/10.2337/diabetes.48.5.1061

Zobrazit plný text záznamu

The association of the human herpesvirus-6 and MS

Autor: J E Whitman, G Cu, Marjaleena Koskiniemi, J E Friedman, Mark A. Edgar, Antti Vaheri, John B. Zabriskie, Michael J. Lyons, D V Ablashl

Publikováno v: Multiple Sclerosis. 5:355-362

Given the clinical and pathological nature of multiple sclerosis (MS), a viral infection has long been hypothesized as part of the etiology. In this study we investigated the possibility that the human herpesvirus-6 (HHV-6) is present in a dormant or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0c3988f8837d89d740ad64de1f3858
https://doi.org/10.1191/135245899678846311

Zobrazit plný text záznamu

Immunolocalization of glucose transporter GLUT4 within human skeletal muscle

Autor: J. E. Friedman, R. W. Dudek, D. S. Whitehead, D. L. Downes, W. R. Frisell, J. F. Caro, G. L. Dohm

Publikováno v: Diabetes. 40:150-154

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a33e07f979fe42c540c3204c108b018c
https://doi.org/10.2337/diabetes.40.1.150

Zobrazit plný text záznamu

Leptin administration prevents spontaneous gestational diabetes in heterozygous Lepr(db/+) mice: effects on placental leptin and fetal growth

Autor: H, Yamashita, J, Shao, T, Ishizuka, P J, Klepcyk, P, Muhlenkamp, L, Qiao, N, Hoggard, J E, Friedman

Publikováno v: Endocrinology. 142(7)

Gestational diabetes mellitus (GDM) results from an interaction between susceptibility genes and the diabetogenic effects of pregnancy. During pregnancy, mice heterozygous for the lepin receptor (db/+) gain more weight, are glucose intolerant, and pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a6211d7a0e43c82855a31a72e0515ef5
https://pubmed.ncbi.nlm.nih.gov/11416008

Zobrazit plný text záznamu

The chicken B-cell receptor complex and its role in avian B-cell development

Autor: C E, Sayegh, S L, Demaries, K A, Pike, J E, Friedman, M J, Ratcliffe

Publikováno v: Immunological reviews. 175

The bursa of Fabricius is critical to normal B-lymphocyte development in birds. During embryonic life, B-cell precursors migrate to the bursal rudiment and those which have undergone productive V(D)J recombination colonize lymphoid follicles and unde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::caf565d39eb778f994d91f37342952d4
https://pubmed.ncbi.nlm.nih.gov/10933603

Zobrazit plný text záznamu

Anti-hyperglycemic activity of moxonidine: metabolic and molecular effects in obese spontaneously hypertensive rats

Autor: J E, Friedman, T, Ishizuka, S, Liu, C J, Farrell, R J, Koletsky, D, Bedol, P, Ernsberger

Publikováno v: Blood pressure. Supplement. 3

Hypertension and insulin resistance are often part of a complex set of abnormalities including obesity, hyperlipidemia, and glucose intolerance, described as syndrome X. Besides a common genetic basis, insulin resistance and hypertension might be lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::637267249862aed1acd5948dca40c98f
https://pubmed.ncbi.nlm.nih.gov/10321453

Zobrazit plný text záznamu

Mechanisms of antihyperglycemic effects of moxonidine in the obese spontaneously hypertensive Koletsky rat (SHROB)

Autor: P, Ernsberger, T, Ishizuka, S, Liu, C J, Farrell, D, Bedol, R J, Koletsky, J E, Friedman

Publikováno v: The Journal of pharmacology and experimental therapeutics. 288(1)

Increased activity of the sympathetic nervous system may be a critical factor in the development of impaired insulin secretion and insulin resistance. We studied the chronic effects of sympathetic inhibition with moxonidine on glucose metabolism in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::26af649f336bb7e003a1b20f42a05780
https://pubmed.ncbi.nlm.nih.gov/9862764

Zobrazit plný text záznamu

Role of acetylated gangliosides on neurite extension

Autor: R, Mendez-Otero, J E, Friedman

Publikováno v: European journal of cell biology. 71(2)

We have investigated the role of 9-O-acetylated gangliosides identified by the Jones monoclonal antibody (Jones mAb) in the elongation of neurites extended by neurons of embryonic rat dorsal root ganglia (DRG) explants grown on laminin substratum. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::87a442a545ca225a0e54ea687d62d5ff
https://pubmed.ncbi.nlm.nih.gov/8905297

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání