Zobrazeno 1 - 10
of 228
pro vyhledávání: '"J E Fothergill"'
Autor:
J E Fothergill, Nicholas C. Price, Jacqueline Nairn, Linda A. Fothergill-Gilmore, Graeme Walker, Bryan Dunbar
Publikováno v:
Biochemical Journal. 297:603-608
The amino acid sequence of the monomeric 2,3-bisphosphoglycerate (BPG)-dependent phosphoglycerate mutase (PGAM) from the fission yeast Schizosaccharomyces pombe has been determined. Amino acid sequencing of proteolytic fragments of the enzyme showed
Publikováno v:
Human Heredity. 43:155-158
The polymerase chain reaction and nucleotide sequencing have been used to characterise a single base substitution (CAG → TAG) at nucleotide 16842 in the C1-inhibitor gene in the affected members of a single family with type I C1-inhibitor deficienc
Publikováno v:
The Journal of pathology. 185(3)
The matrix metalloproteinases (MMPs) are a family of closely related proteolytic enzymes which are involved in the degradation of different components of the extracellular matrix. There is increasing evidence to indicate that individual MMPs have an
Publikováno v:
Current eye research. 16(7)
To isolate and sequence cDNA for bovine rim protein, a large membrane-bound glycoprotein found in photoreceptor outer segments.Bovine rim protein was N-terminally sequenced (22 residues) and fragments were prepared by partial proteolysis. Two interna
Publikováno v:
Nature medicine. 2(4)
Colorectal cancer is one of the commonest malignant tumors and has a relatively poor prognosis. The outcome depends on the extent of local and particularly metastatic tumor spread. The matrix metalloproteinases (MMPs) are a family of closely related
Publikováno v:
Proceedings. International Conference on Intelligent Systems for Molecular Biology. 3
The sequential assignment of protein 2D NMR data has been tackled by many automated and semi-automated systems. One area that these systems have not tackled is the searching of the TOCSY spectrum looking for cross peaks and chemical shift values for
Publikováno v:
Human heredity. 43(3)
The polymerase chain reaction and nucleotide sequencing have been used to characterise a single base substitution (CAG--TAG at nucleotide 16842 in the C1-inhibitor gene in the affected members of a single family with type I C1-inhibitor deficiency. T
Autor:
G. D. Birnie, K. Whaley, A. R. McPhaden, P. E. Carter, David F. Lappin, Peng-Lee Yap, J. E. Fothergill
Publikováno v:
European Journal of Clinical Investigation. 19:45-52
Monocytes of seven out of eight patients with type 1 C1-inhibitor (C1-inh) deficiency (HAE) produced 40% as much C1-inh as monocytes from normal donors (controls). In contrast, monocytes from three patients with type 2 and three patients with acquire
Publikováno v:
Biochemical Journal. 263:301-304
Purified pea (Pisum sativum) cotyledon F1-ATPase contains six subunits rather than the five usually reported for F1-ATPases. The additional 26.5 kDa (delta) subunit is shown by immunoblotting and N-terminal amino acid sequencing to be similar to bovi
Publikováno v:
Biochemical Journal. 183:573-578
The fourth component of bovine complement, C4, was cleaved specifically by subcomponent C1s to produce two fragments, C4a and C4b. The smaller, C4a, was isolated in pure form and is a peptide of 9500 mol.wt. containing approx. 84 amino acids and no d