Zobrazeno 1 - 10
of 124
pro vyhledávání: '"J E, van Lier"'
Optimizing pH-responsive Polymeric Micelles for Drug Delivery in a Cancer Photodynamic Therapy Model
Publikováno v:
Journal of Drug Targeting. 10:429-437
Different pH-sensitive, randomly- and terminally-alkylated N-isopropylacrylamide (NIPAM) copolymers were synthesized and used to prepare pH-responsive polymeric micelles (PM). These copolymers were modified from previously-studied copolymers by incor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e93db8ece5d3c28b6fa93b202de9d87b
https://doi.org/10.1080/1061186021000001887
https://doi.org/10.1080/1061186021000001887
Internalisation enhances photo-induced cytotoxicity of monoclonal antibody-phthalocyanine conjugates
Autor:
Magali Carcenac, Réjean Langlois, Véronique Garambois, Nancy E. Hynes, Ch Larroque, F Glaussel, André Pèlegrin, Mylène Dorvillius, J. E. Van Lier
Publikováno v:
British Journal of Cancer
Immunophototherapy of cancer combines the specificity of a monoclonal antibody (MAb) to an overexpressed tumor marker with the phototoxic properties of the conjugated dye. To analyze the potential role of internalisation of the dye on photo-induced c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715c4020fe67b0c8d265a0bb095d4194
https://doi.org/10.1054/bjoc.2001.2170
https://doi.org/10.1054/bjoc.2001.2170
Publikováno v:
Journal of Pharmacy and Pharmacology. 53:155-166
pH-sensitive polymeric micelles of randomly and terminally alkylated N-isopropylacrylamide copolymers were prepared and characterized. Aluminium chloride phthalocyanine (AlClPc), a second generation sensitizer for the photodynamic therapy of cancer,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abadfa0fbc9d0cef69c601c427c5667
https://doi.org/10.1211/0022357011775352
https://doi.org/10.1211/0022357011775352
Autor:
J. E. Van Lier, Wesley M. Sharman
Publikováno v:
Journal of Porphyrins and Phthalocyanines. :441-453
Palladium catalysts offer a rich and highly versatile chemistry for the synthesis of novel porphyrins and phthalocyanines. These mild and flexible reactions have been used extensively in the preparation of interesting porphyrins and phthalocyanines,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b9691fb4b5a5343644b22e558b697b6
https://doi.org/10.1002/1099-1409(200008)4:5<441::aid-jpp275>3.0.co
https://doi.org/10.1002/1099-1409(200008)4:5<441::aid-jpp275>3.0.co
Publikováno v:
British Journal of Cancer
The potential use of unsubstituted aluminium phthalocyanine (AlClPc) as a sensitizer for photodynamic therapy (PDT) of cancer has not been fully exploited in spite of its higher efficiency as compared to the sulphonated derivatives. This is largely d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153dc7c0c650d7b45c31dd99d63b6dd5
https://doi.org/10.1038/sj.bjc.6690557
https://doi.org/10.1038/sj.bjc.6690557
Autor:
D. Lexa, Thierry Fournier, C. La Madeleine, D. Houde, Réjean Langlois, Z. Liu, J. E. Van Lier, N. Brasseur, Thu-Hoa Tran-Thi
Publikováno v:
The Journal of Physical Chemistry A. 103:1179-1186
We report the novel cooperative properties of a complex obtained by self-assembling in solution a tetracationic cobalt porphyrin, CoIIP4+, and a tetraanionic sulfoaluminum phthalocyanine, AlIIIPc4-. In the ground state, the complex displays a charge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8794de43c23702e497cec915f0c5eb6
https://doi.org/10.1021/jp983936r
https://doi.org/10.1021/jp983936r
Publikováno v:
Journal of Porphyrins and Phthalocyanines. :191-199
Aluminium phthalocyanines sulfonated to a different degree ( AlPcS n) and consisting of various isomeric species were studied by spectroscopic techniques to determine their tendencies to form dimers and aggregates. These characteristics were compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66d7b65bb64d9d7a342af00534b093c
https://doi.org/10.1002/(sici)1099-1409(199805/06)2:3<191::aid-jpp65>3.0.co
https://doi.org/10.1002/(sici)1099-1409(199805/06)2:3<191::aid-jpp65>3.0.co
Publikováno v:
Nuclear Medicine and Biology. 24:151-164
The synthesis and brain uptake in mice of the radioiodinated derivatives of N,N-dimethyl-N'-(iododimethoxyphenyl)-1,3-propanediamine, as well as the N-substituted derivatives of (iodoalkylphenyl)isopropyl, iodoalkylphenylethylamine and 3,4-(methylene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b563d619de24cef4033ac197b7a1ea0
https://doi.org/10.1016/s0969-8051(96)00187-4
https://doi.org/10.1016/s0969-8051(96)00187-4
Publikováno v:
European Journal of Medicinal Chemistry. 32:21-26
Summary Photodynamic therapy (PDT) is a treatment modality for a number of human neoplasms. The drug preparation most widely used in current clinical trials is photofrin. Photofrin lacks definite structure and as a result the interpretation of its ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb7a1bc32ae25fb589a58f02ded1c2fa
https://doi.org/10.1016/s0223-5234(97)84358-9
https://doi.org/10.1016/s0223-5234(97)84358-9
Publikováno v:
British Journal of Cancer
Zinc phthalocyanine (ZnPc) is a second-generation photosensitiser for the photodynamic therapy (PDT) of cancer. Unsubstituted ZnPc is, however, highly insoluble in most common solvents, and for clinical applications the material needs to be incorpora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cdfa395097abb2e55007ddf388f970f
https://doi.org/10.1038/bjc.1996.649
https://doi.org/10.1038/bjc.1996.649