Zobrazeno 1 - 10
of 15
pro vyhledávání: '"J E, Wikberg"'
Publikováno v:
Biochemical pharmacology. 61(5)
The pro-opiomelanocortin-derived peptide alpha-melanocyte-stimulating hormone (alpha-MSH) mediates broad anti-inflammatory and immunomodulatory effects, which include inhibition of the production and release of proinflammatory cytokines and nitric ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6426bda529b80be78a7be261cc84652
https://pubmed.ncbi.nlm.nih.gov/11239505
https://pubmed.ncbi.nlm.nih.gov/11239505
Publikováno v:
The European journal of neuroscience. 13(2)
In recent years a male group of anabolic-androgenic steroid misusers has been identified to share socio-demographic and personality related background factors with misusers of psychotropic substances, as well as being involved in habits of multiple d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b0f410ed9714a89d86f5cc89024ba16
https://pubmed.ncbi.nlm.nih.gov/11168533
https://pubmed.ncbi.nlm.nih.gov/11168533
Publikováno v:
Acta physiologica Scandinavica. 167(2)
The behavioural effects induced by alpha-, gamma1- and gamma2-MSH peptides (0.3 and 3 nmole per rat) injected into the left ventral tegmental area (VTA) of rats were compared. alpha- and gamma1-MSH caused grooming of comparable magnitude, and also ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05fbea33bc08177375495b258b4cc4c2
https://pubmed.ncbi.nlm.nih.gov/10571544
https://pubmed.ncbi.nlm.nih.gov/10571544
Publikováno v:
British journal of pharmacology. 128(5)
1. The potential for the N-hydroxyguanidine compound PR5 (N-(3, 4-dimethoxy-2-chlorobenzylideneamino)-N'-hydroxyguanidine) as a cardioprotective agent in heart ischaemia and reperfusion injury was investigated using rat models. 2. Administration of 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a67d0259ffecc29efbae7af91a8acd27
https://pubmed.ncbi.nlm.nih.gov/10556947
https://pubmed.ncbi.nlm.nih.gov/10556947
Autor:
G V, Skuladottir, L, Jonsson, J O, Skarphedinsson, F, Mutulis, R, Muceniece, A, Raine, I, Mutule, J, Helgason, P, Prusis, J E, Wikberg, H B, Schiöth
Publikováno v:
British journal of pharmacology. 126(1)
1. We designed and synthesized several novel cyclic MSH analogues and tested their affinities for cells expressing the MC1, MC3, MC4 and MC5 receptors. 2. One of the substances HS028 (cyclic [AcCys11, dichloro-D-phenylalanine14, Cys18, Asp-NH2(22)]-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78b6a6c0a6118c5f0543b0601b65595e
https://pubmed.ncbi.nlm.nih.gov/10051117
https://pubmed.ncbi.nlm.nih.gov/10051117
Publikováno v:
Biochemical pharmacology. 56(9)
The mechanism for formation of high-affinity binding of 1-(2,6-dichlorobenzylidene-amino)-3-hydroxyguanidine (guanoxabenz) to alpha2-adrenoceptors was studied in particulate fractions from the rat spleen. The proportion of apparent high versus low-af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75bb530ccbe8d704877453bea656b436
https://pubmed.ncbi.nlm.nih.gov/9802320
https://pubmed.ncbi.nlm.nih.gov/9802320
Publikováno v:
Biochemical pharmacology. 56(9)
The mechanism for formation of high affinity binding of guanoxabenz (1-(2,6-dichlorobenzylidene-amino)-3-hydroxyguanidine) to alpha2-adrenoceptors by the rat spleen cytosol was studied. We report here that the spleen cytosolic fraction mediated the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ddc3335e1a49d9b99b43fa5fb9ff1aa
https://pubmed.ncbi.nlm.nih.gov/9802321
https://pubmed.ncbi.nlm.nih.gov/9802321
Publikováno v:
European journal of pharmacology. 343(1)
The Kd values of the recently introduced radioligand [3H]RS79948-197 ((8a R,12aS,13a-S)-5,8,8a,9,10,11,12,12a,13,13a-decahydro-3-metho xy-12-(ethylsulphonyl)-6H-isoquino[2,1-g][1,6]naphthyridine) were determined for the recombinant human and rat alph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d759072123423ad7fbe347c1acd767a4
https://pubmed.ncbi.nlm.nih.gov/9551719
https://pubmed.ncbi.nlm.nih.gov/9551719
Publikováno v:
Second messengers and phosphoproteins. 12(4)
The sensitivity of the radioimmunoassay for cyclic GMP has been improved to readily detect attomole (200-300) amounts of the nucleotide in tissue extracts. The improved sensitivity has been achieved by using a high specific radioactivity [125I] cycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ecc0ef79903d1ed39abcdb3db7f2dd48
https://pubmed.ncbi.nlm.nih.gov/2854558
https://pubmed.ncbi.nlm.nih.gov/2854558
Publikováno v:
Biochemical pharmacology. 32(21)
An improved method for the solubilization of the alpha 1-adrenergic receptors in rat liver, utilizing digitonin, glycerol and sonication, is described. The yield of solubilized receptors was approximately 20%. The soluble receptors showed characteris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a363ffb5798419d8c2a27f07662aceea
https://pubmed.ncbi.nlm.nih.gov/6139112
https://pubmed.ncbi.nlm.nih.gov/6139112