Zobrazeno 1 - 10
of 25
pro vyhledávání: '"J E, Vena"'
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(8)
A role for alcohol consumption in lung cancer etiology has been suggested in some studies, but this possible relationship has been often regarded with skepticism, with any indication of an association being attributed to confounding by cigarette smok
Autor:
J E, Vena, J M, Weiner
Publikováno v:
International journal of occupational medicine and environmental health. 12(4)
The ability of epidemiology to determine the relationships between health and environmental insults has become exceedingly difficult. The multifactorial nature of disease and the diversity of the insults, which include biologic, physical, social and
Autor:
K B, Moysich, J L, Freudenheim, J A, Baker, C B, Ambrosone, E D, Bowman, E F, Schisterman, J E, Vena, P G, Shields
Publikováno v:
Molecular carcinogenesis. 27(1)
Apolipoprotein E (apoE) is a polymorphic gene involved in lipid metabolism with three common variant alleles (epsilon2, epsilon3, and epsilon4). The epsilon4 allele has been associated with elevated levels of cholesterol as well as greater risk of co
Autor:
J L, Freudenheim, C B, Ambrosone, K B, Moysich, J E, Vena, S, Graham, J R, Marshall, P, Muti, R, Laughlin, T, Nemoto, L C, Harty, G A, Crits, A W, Chan, P G, Shields
Publikováno v:
Cancer causescontrol : CCC. 10(5)
Because alcohol dehydrogenase 3 (ADH3) is rate-limiting in alcohol oxidation and is polymorphic, we examined ADH3 genotype in relation to alcohol intake and breast cancer risk.We conducted a case-control study among Caucasian women aged 40-85 with in
Autor:
K B, Moysich, P, Mendola, E F, Schisterman, J L, Freudenheim, C B, Ambrosone, J E, Vena, P G, Shields, P, Kostyniak, H, Greizerstein, S, Graham, J R, Marshall
Publikováno v:
American journal of industrial medicine. 35(3)
Polychlorinated biphenyls (PCBs) have been associated with a variety of health outcomes. Enhanced laboratory techniques can provide a relatively large number of individual PCB congeners for investigation. However, to date there are no established fra
Autor:
C B, Ambrosone, J L, Freudenheim, P A, Thompson, E, Bowman, J E, Vena, J R, Marshall, S, Graham, R, Laughlin, T, Nemoto, P G, Shields
Publikováno v:
Cancer research. 59(3)
Oxidative stress, resulting from the imbalance between prooxidant and antioxidant states, damages DNA, proteins, cell membranes, and mitochondria and seems to play a role in human breast carcinogenesis. Dietary sources of antioxidants (chemical) and
Autor:
K B, Moysich, P G, Shields, J L, Freudenheim, E F, Schisterman, J E, Vena, P, Kostyniak, H, Greizerstein, J R, Marshall, S, Graham, C B, Ambrosone
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 8(1)
In experimental systems, polychlorinated biphenyls (PCBs) induce cytochrome P4501A1 (CYP1A1), which is involved in metabolism of steroid hormones and polycyclic aromatic hydrocarbons in humans. A genetic polymorphism coding for a valine to isoleucine
Autor:
S A, Petralia, J E, Vena, J L, Freudenheim, A, Michalek, M S, Goldberg, A, Blair, J, Brasure, S, Graham
Publikováno v:
American journal of industrial medicine. 35(2)
Contrasting results have been published regarding the risk of breast cancer among teachers and nurses. Confounding by reproductive factors may explain the increased risk observed among women in these occupations as information on those factors were n
Autor:
P, Mendola, K B, Moysich, J L, Freudenheim, P G, Shields, E F, Schisterman, S, Graham, J E, Vena, J R, Marshall, C B, Ambrosone
Publikováno v:
Epidemiology (Cambridge, Mass.). 9(6)
Maternal smoking increases the risk of spontaneous abortion. Polymorphic N-acetyltransferase (NAT2) and glutathione S-transferase (GSTM1) affect metabolism of some mutagens found in tobacco smoke. Genotypes and smoking were studied in women with at l
Autor:
P A, Thompson, P G, Shields, J L, Freudenheim, A, Stone, J E, Vena, J R, Marshall, S, Graham, R, Laughlin, T, Nemoto, F F, Kadlubar, C B, Ambrosone
Publikováno v:
Cancer research. 58(10)
Polymorphic catechol-O-methyltransferase (COMT) catalyzes the O-methylation of estrogen catechols. In a case-control study, we evaluated the association of the low-activity allele (COMT(Met)) with breast cancer risk. Compared to women with COMT(Val/V