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Autor:
Veronica J. Garcia, Laperle Alexander, Zhan Shu, Matthew Jones, Maria G. Banuelos, K. M. Roxas, Clive N. Svendsen, Pablo Avalos, M. Tagliati, Samuel Sances, Victoria Dardov, Ritchie Ho, Ramachandran Murali, J. E. Van Eyk, Yucer Nur, A. N. Fulton, N. T. Maidment, D. West
Publikováno v:
Nature Medicine. 26:289-299
Young-onset Parkinson's disease (YOPD), defined by onset at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8acea9615c428aeb8b01e19fc0e2c7a7
https://doi.org/10.1038/s41591-019-0739-1
https://doi.org/10.1038/s41591-019-0739-1
Autor:
Daniel Soetkamp, Peter J. Kilfoil, Aleksandra Binek, G. de Couto, J. E. Van Eyk, Amy D. Bradshaw, Joshua I. Goldhaber, Eduardo Marbán, Ronald J. Holewinski, Vidya Venkatraman, Rowann Mostafa, Michael R. Zile, Romain Gallet
IntroductionHeart failure with preserved ejection fraction (HFpEF) is characterized by diastolic dysfunction, pulmonary congestion and exercise intolerance. Previous preclinical studies show that treatment with cardiosphere-derived cells (CDCs) impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82da525e7ce7b5ac861398f7a9085c90
https://doi.org/10.1101/2021.09.06.456608
https://doi.org/10.1101/2021.09.06.456608
Autor:
A H, Laperle, S, Sances, N, Yucer, V J, Dardov, V J, Garcia, R, Ho, A N, Fulton, M R, Jones, K M, Roxas, P, Avalos, D, West, M G, Banuelos, Z, Shu, R, Murali, N T, Maidment, J E, Van Eyk, M, Tagliati, C N, Svendsen
Publikováno v:
Nature medicine. 26(2)
Young-onset Parkinson's disease (YOPD), defined by onset at50 years, accounts for approximately 10% of all Parkinson's disease cases and, while some cases are associated with known genetic mutations, most are not. Here induced pluripotent stem cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b72ec0561c46baac5edf88d8c51c77d7
https://pubmed.ncbi.nlm.nih.gov/32282958
https://pubmed.ncbi.nlm.nih.gov/32282958
Autor:
Joan M. Bathon, Justyna Fert-Bober, Jon T. Giles, Jeremy Sokolove, J. E. Van Eyk, Erin L. Crowgey
Publikováno v:
Protein Deimination in Human Health and Disease ISBN: 9783319582436
Pathological protein citrullination has been associated with a range of diseases including multiple sclerosis, Alzheimer’s disease, rheumatoid arthritis (RA), psoriasis, prion disease, liver fibrosis and cancers. This review will focus primarily on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03c9ae4166339c718a1b0f7af476692e
https://doi.org/10.1007/978-3-319-58244-3_12
https://doi.org/10.1007/978-3-319-58244-3_12
Autor:
J. Craig Hunter, Veronica Lopez, Timothy S. Lancaster, Edward G. Lakatta, J. E. Van Eyk, Donna H. Korzick, Sarah J. Jefferson
Publikováno v:
Physiological Genomics. 44:957-969
The incidence of myocardial infarction rises sharply at menopause, implicating a potential role for estrogen (E2) loss in age-related increases in ischemic injury. We aimed to identify quantitative changes to the cardiac mitochondrial proteome of agi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3301b18d3f0f7a0888adac786b35d73
https://doi.org/10.1152/physiolgenomics.00184.2011
https://doi.org/10.1152/physiolgenomics.00184.2011
Publikováno v:
Pharmacological Research. 55:511-522
Recent developments in the field of protein separation allows for the analysis of qualitative and quantitative global protein changes in a particular state of a biological system. Due to the enormous number of proteins potentially present in a cell,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7149e25e456664b13d6fcd6ff4498a0a
https://doi.org/10.1016/j.phrs.2007.04.012
https://doi.org/10.1016/j.phrs.2007.04.012
Autor:
Paul D. Allen, C. C. Liew, Raimond L. Winslow, C.G. dos Remedios, J. E. Van Eyk, Michael J. Dunn
Publikováno v:
Journal of Muscle Research and Cell Motility. 24:251-261
Unraveling the molecular complexities of human heart failure, particularly end-stage failure, can be achieved by combining multiple investigative approaches. There are several parts to the problem. Each patient is the product of a complex set of gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::844e4491fc96f04da8cfb133300ad6cd
https://doi.org/10.1023/a:1025433721505
https://doi.org/10.1023/a:1025433721505
Autor:
AGNETTI, GIULIO, GUARNIERI, CARLO, CALDARERA, CLAUDIO MARCELLO, V. Halperin Kuhns, Y. Guo, S. Sheng, Z. Fu, F. Nicolini, T. Gherli, D. A. Kass, G. F. Tomaselli, J. E. Van Eyk
Desmin constitutes the intermediate filaments (IFs) cytoskeleton in cardiac myocytes. Novel roles of the IFs, including the formation of toxic aggregates similar to those found in neurodegenerative diseases, have been recently linked to heart failure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4094::c16bfa0b7edb1b954c2d034e0f100311
http://hdl.handle.net/11585/100431
http://hdl.handle.net/11585/100431