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The roles of CD11/CD18 and ICAM-1 in acute Pseudomonas aeruginosa-induced pneumonia in mice

Autor: L, Qin, W M, Quinlan, N A, Doyle, L, Graham, J E, Sligh, F, Takei, A L, Beaudet, C M, Doerschuk

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 157(11)

Neutrophil accumulation in response to Pseudomonas aeruginosa in the lungs is mediated through CD11/CD18. This study determined the roles of CD11a, CD11b, and intercellular adhesion molecule (ICAM)-1 in P. aeruginosa-induced pneumonia and compared th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a32425391ebec281812b17cb900e07e
https://pubmed.ncbi.nlm.nih.gov/8943409

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An initiation codon mutation in CD18 in association with the moderate phenotype of leukocyte adhesion deficiency

Autor: J E, Sligh, M Y, Hurwitz, C M, Zhu, D C, Anderson, A L, Beaudet

Publikováno v: The Journal of biological chemistry. 267(2)

Leukocyte adhesion deficiency (LAD) is an autosomal recessive disease caused by mutations in the CD18 gene which codes for the beta 2 integrin subunit. We studied two patients, the first of which had a moderate LAD phenotype and expressed only 9% of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::57b246ac64bdb5f7caf61aca2a9ae94e
https://pubmed.ncbi.nlm.nih.gov/1346132

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